The establishment of a nitrogen-fixing root nodule on legumes requires the induction of mitotic activity of cortical cells leading to the formation of the nodule primordium and the infection process by which the bacteria enter this primordium. Several genes are up-regulated during these processes, among them ENOD40. Here it is shown, by using gene-specific knock-down of the two Medicago truncat...

We developed a palpation simulator for training on muscle palpation techniques for myofascial pain syndrome. This simulator consisted of two layers that resemble the hardness of actual human skin-fat and muscle tissues. Furthermore, a muscle nodule model made of urethane rubber was laid in the simulator. Five participants were trained on the palpation technique for localizing the muscle nodule ...

Intramedullary spinal cord abscess (ISCA) is a rare infection of the central nervous system. We describe the magnetic resonance imaging (MRI) findings, including the diffusion-weighted imaging (DWI) findings, of ISCA in a 78-year-old man. The initial conventional MRI of the thoracic spine demonstrated a subtle enhancing nodule accompanied by significant edema. On the follow-up MRI after seven d...

N-acyl homoserine lactones (AHLs) act as quorum sensing signals that regulate cell-density dependent behaviors in many gram-negative bacteria, in particular those important for plant-microbe interactions. AHLs can also be recognized by plants, and this may influence their interactions with bacteria. Here we tested whether the exposure to AHLs affects the nodule-forming symbiosis between legume ...

Lung nodule measurements made with CT imaging are used in clinical practice to assess size changes estimated from serial scans obtained over time to predict the likelihood of malignancy and to monitor the tumor response to treatment. 2 Size measurements need to be accurate and consistent to enable the assessment of nodule changes in a short time interval. Th e precision and accuracy of volume m...

We report a 50-year-old woman whose atypical lung carcinoid presented as a single subcutaneous nodule. Biopsy of the nodule revealed neuroendocrine carcinoma likely from the lungs. Imaging studies revealed masses in lungs, pelvis and right axilla, and a seizure a few months later lead to discovery of brain metastasis. This case illustrates that an apparently innocuous subcutaneous nodule could ...

Nodule development directly affects nitrogen fixation efficiency during soybean growth. Although abundant genome-based information related to nodule development has been released and some studies have reported the molecular mechanisms that regulate nodule development, information on the way nodule genes operate in nodule development at different developmental stages of soybean is limited. In th...

PURPOSE The presence of two or more Lisch nodules (melanocytic hamartomas of the iris) is one of seven diagnostic criteria for neurofibromatosis type 1 (NF1), a common monogenic disorder of dysregulated neurocutaneous growth. The hypothesis that Lisch nodules arise secondary to exposure to ultraviolet (UV) radiation from sunlight was investigated. METHODS Lisch nodule burden was mapped and qu...

OBJECTIVE To evaluate how changes in lung volume affect volumetric measurements of lung nodules using a multi-detector row CT. MATERIALS AND METHODS Ten subjects with asthma or chronic bronchitis who had one or more lung nodules were included. For each subject, two sets of CT images were obtained at inspiration and at expiration. A total of 33 nodules (23 nodules > or =3 mm) were identified a...

The effect of boron (B) deficiency on cell permeability and connected with that, changes in soluble sugars, amino acids and ureides partitioning between root and nodule apoplast and symplast of N2 fixing soybean plants grown in water culture were studied. Exposure of a transient 10 -day B deficiency stress was found to inhibit nodule number and to increase nodule dry weight. The formation of la...