background: the aim of this study was to compare the effects of diode laser irradiation on wound healing in oral rat mucosa and also to measure the amount of inducible nitric oxide synthase (inos) and endothelial nos (enos) on oral wound healing. healing was assessed by histology and the amounts of enos and inos were measured by real‑time polymerase chain reaction (pcr). materials and methods: ...

the genus artemisia is estimated to comprise over 800 species with anti-cancer, anti-fungal, anti-oxidant and anti-inflammatory properties. artemisia fragrans ( a. fragrans ), a species that belongs to genus artemisia , is rich in monoterpenes and sesquiterpenes derivatives. due to anti-inflammatory properties of monoterpenes and sesquiterpenes, we aimed to investigate the effect of a. fragrans...

Experiments were designed to determine whether normal fluctuations in sex steroid hormones alter gene transcription for endothelial nitric oxide synthase (NOS) and preproendothelin-1 (prepro-ET-1). Aortic endothelial cells were removed from adult, gonadally intact male and female or ovariectomized Yorkshire pigs. Endothelial cells were prepared for Northern blot analysis, Western blot analysis ...

Tuberculosis (TB) is one of the most common infectious diseases in the world. Mycobacterium tuberculosis infection leads to pulmonary active disease in approximately 5-10% of exposed individuals. Both bacteria- and host-related characteristics influence latent infection and disease. Host genetic predisposition to develop TB may involve multiple genes and their polymorphisms. It was reported pre...

By measurements of NO2-/NO3- (NOx) production and Northern blot analysis, we studied the effects of a membrane-permeable cAMP derivative, 8-bromo-cAMP, on the expression of inducible nitric oxide synthase (iNOS) gene and the synthesis of NOx in cultured rat vascular smooth muscle cells (VSMCs). 8-bromo-cAMP stimulated NOx production and increased steady-state levels of iNOS mRNA in rat VSMC in ...

eNOS: endothelial nitric oxide synthase Hcy: homocysteine NO: nitric oxide VEGF: vascular endothelial growth factor INTRODUCTION This report shows a positive therapeutic effect of high-dose folic acid plus vitamins B6 and B12 on a patient with palmar plantar pustulosis. Improvement was likely through modulation of homocysteine (Hcy) and nitric oxide (NO) synthase metabolic pathways, and by inhi...

Hypertension IS accompanied by architectural changes m the kidney, heart, and vessels that are often maladaptlve and can eventually contribute to end-organ disease such as renal failure, heart failure, and coronary disease Nitric oxide, an endogenous vasodllator and antlthrombotlc agent synthesized m the endothehum by a constltutlve mtnc oxide synthase, mhlblts growth-related responses to injur...