This study aimed to elucidate associations between stroke onset and severity as well as chronotype (phase of entrainment) and internal time of stroke. Fifty-six first-ever ischemic stroke patients participated in a cross-sectional study assessing chronotype (mid-sleep on work-free days corrected for sleep deficit on workdays; MSFsc) by applying the Munich ChronoType Questionnaire (MCTQ). The MC...

Lesion analysis reveals causal contributions of brain regions to mental functions, aiding the understanding of normal brain function as well as rehabilitation of brain-damaged patients. We applied a novel lesion inference technique based on game theory, Multi-perturbation Shapley value Analysis (MSA), to a large clinical lesion dataset. We used MSA to analyze the lesion patterns of 148 acute st...

OBJECTIVE To evaluate the risk factors and comorbid conditions associated with the development of pneumonia in patients with acute stroke. To determine the independent predictors of pneumonia. METHOD Retrospective study from July to December 2011. We reviewed all medical charts with diagnosis of stroke. RESULTS 159 patients (18-90 years) were admitted. Prevalence of pneumonia was 32%. Pneum...

Diagnosis of posterior circulation stroke may be challenged. National Institutes Health Stroke Scale (NIHSS) and brain imaging (non-contrast computed tomography-CT) are used for diagnosis; evaluation on remains a limit NIHSS, the value non-contrast CT (NCCT) is limited due to artifacts caused by bones base skull. We tested validity prognostic Alberta Program Early Score (pc-ASPECTS) in patients...

BACKGROUND AND PURPOSE Clot dissolution with tissue plasminogen activator (tPA) can lead to early clinical recovery after stroke. Transcranial Doppler (TCD) with low MHz frequency can determine arterial occlusion and monitor recanalization and may potentiate thrombolysis. METHODS Stroke patients receiving intravenous tPA were monitored during infusion with portable TCD (Multigon 500M; DWL Mul...

Background and Purpose—No stroke scale has been validated as an outcome measure using data from a clinical trial demonstrating a positive therapeutic effect. Therefore, we proposed to use data from the National Institute of Neurological Disorders and Stroke (NINDS) tPA Stroke Trial to determine whether the National Institutes of Health Stroke Scale (NIHSS) was valid in patients treated with tis...