The present study was designed to investigate the possible insulinotropic properties of Nigella sativa L. (N. sativa) oil in Streptozotocin plus Nicotinamide-induced diabetes mellitus in hamsters. Nicotinamide was injected intraperitoneally 15min before injection of Streptozotocin intravenously. Oral treatment with N. sativa oil began 4 weeks after induction of diabetes. Serum insulin was measu...

Article Type Original Research Authors Mohebbati R.1 MSc, Abbsnezhad A.2 PhD, Khajavi Rad A.* MD, PhD, Mousavi S.M.1 MSc, Haghshenas M.1 MSc How to cite this article Mohebbati R, Abbsnezhad A, Khajavi Rad A, Mousavi S.M, Haghshenas M. Effect of Hydroalcholic Extract of Nigella sativa on DoxorubicinInduced Functional Damage of Kidney in Rats. Quarterly of the Horizon of Medical Sciences. 2016;22...

Nigella sativa or Black seed (N. sativa L.) is traditionally used for several ailments in many Middle Eastern countries. It is an annual herbaceous plant that belongs to the Ranuculacea family with many beneficial properties as antitumor, antidiabetic, antihypertensive, antioxidative and antibacterial. This work attempted to study the effect of N. sativa seeds powder and oil on atherosclerosis ...

The objective of this study was the evaluation antiarthritic activity as well phytochemical screening Nigella sativa L. seeds extracts in vitro. dosage flavonoids have shown that content found hydroalcoholic extract (134.7 ± 0.289 mg QE / g) significantly higher compared to aqueous (48.495 0.035mg g). phytochemicals analysis revealed presence tannins, saponins and reducing compounds absence alk...

Nigella sativa, known as black seed, has analgesic, anti-inflammatory, antioxidant and anticancer effects. It has been shown to reduce the development of kidney failure when given prior to the use of nephrotoxic drugs particularly due to its antioxidant action. However, as far as the authors could ascertain, there is no human study in literature showing these effects. Here we present a case of ...

background: the task force on plants for fertility regulation in men continued with its program to identify novel prototypes in plants alleged to have fertility regulating properties. nigella sativa   objective: to evaluated the role of alcoholic extract of nigella sativa on fertility potential, pituitary-testicular axis hormones and testosterone in male rats.   materials and methods: 24 male r...

Synthesis of silver nanoparticles using seeds of Nigella sativa as reducing agent was evaluated in this study. Homogenized extract of N. sativa exposed to sunlight gave a better synthesis of nanoparticles when compared to other methods. Antibacterial activity of nanoparticles was studied against urinary tract infection (UTI) causing bacteria by disc diffusion method. Further, the silver nanopar...

Nigella sativa (NS) has been shown to have antioxidant, anti-inflammatory and antiulcer activities in different conditions. The present work was done to investigate the possible effects of Nigella sativa aqueous extracts (NS) on gastric acid secretion in isolated rat stomach. Gastric acid secretion was measured in the isolated rat stomach preparation. The results obtained in vitro experiments s...

Objectives: Nigella sativa is a medicinal plant that has long been used in traditional medicine for treating various conditions. Numerous animal studies provided evidences that the seed may elicit a broad anti-inflammatory/anti-oxidant activity. The aim of the present clinical trial was to evaluate anti-inflammatory and antioxidant properties of Nigella sativa oil in patients with rheumatoid ar...