نتایج جستجو برای: nfat5
تعداد نتایج: 312 فیلتر نتایج به سال:
Recent characterizations of various types of diierentiable generalized monotone maps by Karamardian{ Schaible{Crouzeix and their strengthened versions by Crouzeix{Ferland are extended to the nonsmooth case. For nondiierentiable locally Lipschitz maps necessary and/or suucient conditions for quasimono-tonicity, pseudomonotonicity and strict/ strong pseudomonotonicity are derived. To accomplish t...
The paper introduces exceptional inheritance logic (EIL) for handling inheritance nonmono-tonicity. EIL depends on the idea that an inheritable exception should be part of an exceptional class for which the exception is a default. The introduction of an exceptional class changes nonmonotonic inheritance structures in such a way that ambiguities and connicts can be resolved in certain cases. Fou...
NFκB is a central mediator of inflammation. Present inhibitors of NFκB are mostly based on inhibition of essential machinery such as proteasome and protein kinases, or activation of nuclear receptors; as such, they are of limited therapeutic use due to severe toxicity. Here we report an LPS-induced NFκB enhanceosome in which TonEBP is required for the recruitment of p300. Increased expression o...
The signaling pathways leading to high NaCl-induced activation of the transcription factor tonicity-responsive enhancer binding protein/osmotic response element binding protein (TonEBP/OREBP) remain incompletely understood. High NaCl has been reported to produce oxidative stress. Reactive oxygen species (ROS), which are a component of oxidative stress, contribute to regulation of transcription ...
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