Neurogenesis in the adult hippocampus is an important form of structural plasticity in the brain. Here we report a line of BAC transgenic mice (GAD67-GFP mice) that selectively and transitorily express GFP in newborn dentate granule cells of the adult hippocampus. These GFP(+) cells show a high degree of colocalization with BrdU-labeled nuclei one week after BrdU injection and express the newbo...

OBJECTIVE To evaluate the use of drugs to relieve procedural pain of newborn infants hospitalized in Neonatal Intensive Care Units (NICU) of university hospitals. METHODS A prospective cohort study of all newborn infants hospitalized in four NICU during October 2001. The following data were collected: demographic data of patients; clinical morbidity; number of potentially painful procedures a...

When WHO published the Mother-Baby Package in 1996, mothers and newborn babies were viewed as a dyad, and it was assumed that what was good for the mother was good for the baby. Basic interventions to deal with newborn complications were included, but neonatal mortality received little attention from the broader public health community, or even from the maternal health and child health communit...

The European Resuscitation Council has produced these newborn life support guidelines, which are based on the International Liaison Committee (ILCOR) 2020 Consensus Science and Treatment Recommendations (CoSTR) for Neonatal Life Support. guidelines cover management of term preterm infant. topics covered include an algorithm to aid a logical approach resuscitation newborn, factors before deliver...

CPT1A enzyme deficiency is a rare metabolic disorder of mitochondrial fatty acid oxidation, with late manifestations during infancy or childhood, including hypoketotic hypoglycemia and hepatic encephalopathy. Newborn screening in several countries include pre-symptomatic detection deficiency, which helps early diagnosis better management the disorder. We report here case detected pre-symptomati...

Due to high entry barriers, countries might find it daunting implement the NBS program, especially those just trying start it. This review aims discuss Indonesia’s barriers that hinder newborn screening (NBS) implementation while discussing future implications. Literature in Pubmed and Google Scholar was scoured with keywords such as “Newborn Screening”, “Neonatal “Indonesia”, “Asia Pacific”, “...

By a host of metrics, women and their children have been getting healthier in recent years. Between 1990 and 2013, the annual number of maternal deaths dropped from 523 000 to 289 000. The child mortality story is just as impressive. Since 1990, deaths in children younger than 5 years have declined by 47%. Given the critical role that women and children have in securing a healthy, prosperous, a...

BACKGROUND Indonesia's progress on reducing maternal and newborn mortality rates has slowed in recent years, predominantly in rural areas. To reduce maternal and newborn mortality, access to quality and skilled care, particularly at the facility level, is crucial. Yet, accessing such care is often delayed when maternal and newborn complications arise. Using the "Three Delays" model originated b...

BACKGROUND Tracking aid flows helps to hold donors accountable and to compare the allocation of resources in relation to health need. With the use of data reported by donors in 2015, we provided estimates of official development assistance and grants from the Bill & Melinda Gates Foundation (collectively termed ODA+) to reproductive, maternal, newborn, and child health for 2013 and complete tre...