Parkinson’s disease (PD) is the world’s second-most serious neurodegenerative disorder, affecting millions of people each year. The current techniques used to screen for new PD therapies in-vitro are unable to integrate dopamine detection on chip with long-term differentiated neuron cell culture. We have developed a digital microfluidic system that integrates long-term neuron culture with elect...

new product development (npd) is described in the literature as the transformation of a market opportunity into a product available for sale. in the automotive industry, within the context of iso/ts16949:2002 (the automotive quality management system international standard),  these related to the product realization process (prp) which consists of three main phases such as planning, implementat...

two probiotic bacteria (lb. acidophilus and b. lactis) were immobilized on the alginate coat of strawberry pieces and were added to the prepared sweet non fat dietary stirred yogurt. physico-chemical parameters namely ph value, titratable acidity and synersis along with the viability of probiotic bacteria of the samples were evaluated over the 8 days of storage at 5 ºc at 2 day intervals. a sig...

The presence of the anisakid nematode Hysterothylacium gadi aduncum (Rudolphi, 1802) is reported for the first time in cultured rainbow trout (Oncorhynchus mykiss Walbaum, 1792) as a new host in freshwater farms from Turkey. This marine parasitic nematode is thought to complete the life cycle in fresh water and rainbow trout could act as the definitive host for this parasite under fresh water c...

A series of 2-benzoxazolinone, diazocoumarin and quinazoline derivatives have been shown to inhibit HIV replication in cell culture. To understand the pharmacophore properties of selected molecules and design new anti-HIV agents, quantitative structure–activity relationship (QSAR) study was developed using a descriptor selection approach based on the stepwise method. Multiple linear regression ...

We know a great deal about the development of the mammalian embryo until the time that the blastocyst implants into the uterus. With model organisms such as the mouse, we have also developed a considerable understanding of development immediately around gastrulation as embryos can be recovered at this stage for short-term in vitro culture. However, the intervening period of development remained...

Two probiotic bacteria (Lb. acidophilus and B. lactis) were immobilized on the alginate coat of strawberry pieces and were added to the prepared sweet non fat dietary stirred yogurt. Physico-chemical parameters namely pH value, titratable acidity and synersis along with the viability of probiotic bacteria of the samples were evaluated over the 8 days of storage at 5 ºC at 2 day intervals. A sig...