Primer Cicatricial Alopecias (PCAs) are a group of autoinflammatory disorders characterized by scarring the hair follicle and result is irreversible loss. CD8+ T cells attack epithelial stem (eHFSCs) in bulge follicle, fibrosis ultimately leads to Immune privilege collapse plays role pathogenesis alopecia areata, though its loss not fully characterized. We developed an inducible mouse model tha...

UNLABELLED The cicatricial alopecias encompass a diverse group of disorders characterized by permanent destruction of the hair follicle and irreversible hair loss. Destruction of the hair follicle can result from primary, folliculocentric disease or as a secondary result. This article focuses on the former, or primary cicatricial alopecias. The cause and pathogenesis of many of these disorders ...

The anti-malarial hydroxychloroquine (HCQ) is a common treatment for cicatricial alopecias (CA). Serious adverse events include prolonged QT interval, ventricular arrythmias and irreversible retinopathy. There limited literature on the incidence of in CA patients taking HCQ. A retrospective analysis was performed 60 patients, mean age years, prescribed Alopecia diagnoses included lichen planopi...