Background and objectives. Eugène Devic (1858-1930) made medical and neurological history in 1894 when he described neuromyelitis optica (NMO). This article describes how the concept of this disease has evolved over the centuries since being described by the well-known doctor from Lyon. Methods. To describe the history of NMO, we performed a literature search in PubMed, ScienceDirect, and Googl...

INTRODUCTION Neuromyelitis optica (NMO) is a severe demyelinating syndrome characterized by optic neuritis (ON) and acute myelitis. The NMO spectrum is actually recognized to typically evolve as a relapsing disorder that also includes patients with atypical unilateral ON and those with index events of ON and myelitis occurring weeks or even years apart (Jarius/Wildemann 2013). NMO was previousl...

Irreversible neurological deficit and disability in neuromyelitis optica spectrum disorders (NOSD) are formed as a result of exacerbations, which often life-threatening. Timely diagnosis treatment exacerbations is key task the management this category patients. A unified structured approach to NOSD has not been developed. The purpose article analyze scientific literature data on issue order opt...

We read with interest the article by Glasier et al, “Clinical, Neurodiagnostic, and MR Findings in Children with Spinal and Brain Stem Multiple Sclerosis” (1). In this study, five of seven children with spinal multiple sclerosis (MS) had lesions that extended over three or more segments with concomitant cord swelling. This differs from our experience as well as that of previous authors. Typical...