نتایج جستجو برای: neurofibromatosis type 1

تعداد نتایج: 3649069  

Journal: :Development 1995
T Rosenbaum Y L Boissy K Kombrinck C I Brannan N A Jenkins N G Copeland N Ratner

To identify cell type(s) that might contribute to nerve sheath tumors (neurofibromas) in patients with neurofibromatosis type 1, we generated cell cultures containing neurons. Schwann cells and fibroblasts from transgenic mouse embryos in which the type 1 neurofibromatosis gene was disrupted by homologous recombination (Brannan et al. (1994) Genes Development, 8,1019-1029). Normal fascicle form...

2012
Jill C. Isenberg Alexandra Templer Feng Gao Jeffrey B. Titus David H. Gutmann

Children with neurofibromatosis type 1 are at increased risk for the development of attention problems relative to their unaffected peers. Previous studies have reported deficits in sustained auditory attention, but other aspects of attention, including sustained visual attention, divided attention, response inhibition, and selective attention, have not been consistently documented. In the pres...

Journal: :Journal of child neurology 2013
Amy K Licis Alicia Vallorani Feng Gao Cynthia Chen Jason Lenox Kelvin A Yamada Stephen P Duntley David H Gutmann

Children with neurodevelopmental disorders are at increased risk for sleep issues, which affect quality of life, cognitive function, and behavior. To determine the prevalence of sleep problems in children with the common neurodevelopmental disorder neurofibromatosis type 1, a cross-sectional study was performed on 129 affected subjects and 89 unaffected siblings, age 2 to 17 years, using the Sl...

Journal: :Revista da Associação Médica Brasileira 2016

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