Primary small cell neuroendocrine carcinoma (SCNEC) is a rare high-grade malignant neoplasm with differentiation derived from the urothelium. Herein, we report case which presented symptomatic anaemia secondary to haematuria, complicated acute kidney injury following obstructive uropathy caused by SCNEC, along discussion of clinical presentation, radiological imaging and pathological findings d...

OBJECTIVE No standard treatment has been established for poorly differentiated neuroendocrine carcinoma; the usual recommended treatment is based on the strategy for small cell lung carcinoma. The aim of this study was to evaluate the response of poorly differentiated neuroendocrine carcinoma to the combination of irinotecan and cisplatin in one institution. METHODS We retrospectively reviewe...

Primary neuroendocrine carcinoma of the breast is extremely rare. More than 97% of neuroendocrine tumors occur in the gastrointestinal and respiratory tracts. Three cases that have been operated in our clinic and had a diagnosis of primary neuroendocrine carcinoma of the breast were assessed, along with literature data. Histopathological diagnoses were obtained by preoperative core needle biops...

INTRODUCTION Neuroendocrine carcinoma was a rare kind tumor in gallbladders. So far, there is no consensus of treatment of the gallbladder neuroendocrine carcinoma. CASE PRESENTATION Three patients, 1 male and 2 females, were admitted in our hospital because of right upper quadrant pain. No one complained fever, jaundice, weight loss, or carcinoid syndrome-related symptoms such as diarrhea, f...

endocrine tumors of the pancreas (islet-cell tumors) are rare with neuroendocrine origin. the patient was a 41- year- old man, admitted with chief complains of epigastric mass feeling, dull abdominal pain, lack of appetite and weight loss up to 2-3 kg since 6 months ago. in physical examination, a mass was detected in epigaster and left upper quadrant (luq). in abdominal x-ray, a calcified mass...

neuroendocrine tumors (nets) constitute a heterogeneous group of neoplasms including carcinoids, pancreatic neuroendocrine tumors, pituitary tumors, medullary thyroid carcinoma and phaeochromocytomas. the symptoms and the outcome of nets differ considerably between patients depending on several factors. by labelling tracers with a radioisotope, the tracer acts as a carrier to deliver the radioa...

UNLABELLED While prostatic adenocarcinomas are relatively indolent, some patients with advanced adenocarcinomas recur with small cell neuroendocrine carcinoma which is highly aggressive and lethal. Because glycolysis is a feature of malignancy and the degree of glycolysis generally correlates with tumor aggressiveness, we wanted to compare the metabolic differences and the molecular mechanisms ...

BACKGROUND Neuroendocine carcinoma of the gynecologic tract is rare and poses a significant clinical challenge because of tumor heterogeneity and lack of standardized guidelines for treatment. Ovotestis refers to the histology of a gonad that contains both ovarian follicles and testicular tubular elements. Ovotesticular disorder of sexual development occurs in fewer than 10% of all disorders of...

BACKGROUND Although neuroendocrine tumors are most commonly found in the digestive system, neuroendocrine tumors originating from the bile duct are rare, and neuroendocrine carcinomas derived from the perihilar bile duct are extremely rare. This report presents the clinical course and clinicopathological features of neuroendocrine carcinomas arising from the extrahepatic bile duct. CASE PRESE...

Neuroendocrine tumors rarely occur in the urinary bladder, relatively less than 1% of occurrence, as tumor is very rare, pathogenesis uncertain some authors showed that it from urothelial origin. It can be carcinomatous, subdivided into small cell and large pathology. Small carcinoma bladder a rarity may present at an advanced pathologic stage. No treatment regimens have been standardized for l...