The interactions between cells and nanomaterials at the nanoscale play a pivotal role in controlling cellular behavior ample evidence links cell intercommunication to nanomaterial size. However, little is known about effect of geometry on behavior. To elucidate this extend application cancer theranostics, we have engineered core–shell cobalt–gold nanoparticles with spherical (Co@Au NPs) ellipti...

The main focus of this study is the development an adapted complex variable method with respect to equilibrium point in bistable nonlinear energy sink (NES), which mainly investigated vicinity 1:1 resonance. A simplified chaos trigger model established describe distance between stable phase cycle and pseudo-separatrix. An analytical expression can predict excitation threshold for occurrence. re...

Data preprocessing plays a crucial role in phrase-based statistical machine translation (PB-SMT). In this paper, we show how single-tokenization of two types of multi-word expressions (MWE), namely named entities (NE) and compound verbs, as well as their prior alignment can boost the performance of PB-SMT. Single-tokenization of compound verbs and named entities (NE) provides significant gains ...

Somatic hypermutation (SHM) and class switch recombination (CSR) are initiated in activated B lymphocytes by activation-induced deaminase (AID). AID is thought to make lesions in DNA by deaminating cytidine residues in single-stranded DNA exposed by RNA polymerase during transcription. Although this must occur in the nucleus, AID is found primarily in the cytoplasm. Here we show that AID is act...

The targeted energy transfer (TET) phenomenon has been demonstrated and analyzed between an acoustic medium inside a parallelepiped cavity and a thin viscoelastic membrane that is mounted on one wall of the cavity and that is working as a nonlinear absorber or a nonlinear energy sink (NES). Based on the desired working zone of the NES and the two thresholds of the zone which have been obtained,...

A node-based smoothed finite element method (NS-FEM-T3) using triangular elements and a n-sided polygonal edge-based smoothed FEM (nES-FEM) using polygonal elements is combined to give the smoothed coupled NS/nES-FEM for dynamic analysis of twodimensional (2D) fluid–solid interaction problems based on the pressure–displacement formulation. In the present method, the NS-FEM-T3 is used for the fl...

Tokenization in the bioscience domain is often difficult. New terms, technical terminology, and nonstandard orthography, all common in bioscience text, contribute to this difficulty. This paper will introduce the tasks of tokenization, normalization before introducing BAccHANT, a system built for bioscience text normalization. Casting tokenization / normalization as a problem of punctuation cla...

The Natural Evolution Strategies (NES) family of search algorithms have been shown to be efficient black-box optimizers, but the most powerful version xNES does not scale to problems with more than a few hundred dimensions. And the scalable variant, SNES, potentially ignores important correlations between parameters. This paper introduces Block Diagonal NES (BD-NES), a variant of NES which uses...

Night eating syndrome (NES) is characterized by evening hyperphagia and frequent awakenings accompanied by food intake. Patients with NES display a delayed circadian pattern of food intake but retain a normal sleep-wake cycle. These characteristics initiated the current study, in which the phase and amplitude of behavioral and neuroendocrine circadian rhythms in patients with NES were evaluated...

The recently introduced family of natural evolution strategies (NES), a novel stochastic descent method employing the natural gradient, is providing a more principled alternative to the well-known covariance matrix adaptation evolution strategy (CMA-ES). Until now, NES could only be used for single-objective optimization. This paper extends the approach to the multi-objective case, by first der...