Background Radical prostatectomy (RP) is frequently responsible for erectile dysfunction (ED). Post-RP patients often show insufficient response or treatment failures to PDE5 inhibitor therapy. This study was undertaken to evaluate the acute effects of the soluble guanylate cyclase (sGC) stimulator, BAY 60-4552 and vardenafil administered alone or in combination on erectile responses to electri...

A novel partially implantable system for correction of foot drop has been developed and is being tested in three volunteer subjects. The system consists of a two-channel implantable stimulator, a multi-polar nerve cuff electrode implanted on the peroneal nerve proximal to the knee, and an external system including battery, control and telemetry unit and a heel switch. Although the work is still...

UNLABELLED We describe a modification of the sciatic nerve (SN) block in the popliteal fossa through the lateral approach. After a brief anatomic study using previously reported landmarks, we propose a new needle orientation associated with a double injection technique after identification of the tibial and the common peroneal nerve. Thirty-four patients undergoing ankle or foot surgery were en...

Many methods have been proposed for resuscitation of the newborn but there is as yet no single widely accepted approach to this commonly recurring problem. It is the purpose of this paper to review briefly the electronic methods of resuscitation and to describe animal experiments with a simple electronic apparatus which may be of value for the human newborn. In 1948 Sarnoff et al.' reported ani...

This paper describes a portable, multichannel skeletal muscle stimulator developed for use in research in skeletal muscle cardiac assist (SMCA). The primary features of the stimulator are that it allows selective stimulation through multiple nerve-cuff electrodes and that arbitrary voltage pattems can be delivered to each electrode. The electrodes are electrically isolated from one another to e...

BACKGROUND Exact location of the needle tip during nerve stimulation-guided peripheral nerve blocks is unknown. Using high-frequency ultrasound imaging, we tested the hypothesis that intraneural injection is common with nerve stimulator-guided sciatic nerve (SN) block in popliteal fossa. METHODS Forty-two patients scheduled for hallux valgus repair were studied. Sciatic block at the popliteal...

BACKGROUND Intraneural injection during nerve-stimulator-guided sciatic block at the popliteal fossa may be a common occurrence. Although intraneural injections have not resulted in clinically detectable neurologic injury in small studies in human subjects, intraneural injections result in postinjection inflammation in animal models. This study used clinical, imaging, and electrophysiologic mea...

Migraines affect approximately one billion individuals worldwide. Implanted nerve stimulator devices can provide relief to some who have chronic migraines refractory other treatments. This study defines the change in headache pain severity and frequency following implanted treatment migraineurs. A PRISMA-compliant systematic review of six databases was performed identify all clinical trials tre...