نتایج جستجو برای: nephron
تعداد نتایج: 4732 فیلتر نتایج به سال:
Nephrotic syndrome is an important disease in children and the diagnosis and treatment of its complications is important. Edema is one of these complications which is more common and severe in children and has different treatment in comparison with adults. Treatment of edema in children contains protocols that increase intravascular volume and decrease sodium reabsorption in all par...
At present, special attention is drawn to the study of adaptation aquatic organisms a complex environmental factors precisely at cellular level. It very important structural and functional features kidney, which not only plays key role in osmoregulation, but also makes significant contribution maintaining homeostasis level functioning single nonspecific defense system body. In this aspect, spec...
TO THE EDITOR: In a very interesting recent paper, Tarry-Adkins et al. (6) describe the beneficial effects of slow growth during lactation in the rat. With increasing age, rats nurtured by dams that were fed a low-protein diet during lactation showed, among other favorable effects, no proteinuria in contrast with control male rats that showed progressive urinary protein loss. These results are ...
The maintenance of sodium (Na+) homeostasis is an essential function of the kidney. It is achieved by a variety of transport processes localized all along the highly specialised segments of the nephron. Impairment of these transport mechanisms, and thereby Na+ handling, is associated with disturbed Na+ and water balance, leading to hypertension and oedema. This review focuses on the novel regul...
Nephron reduction is an important factor in the development of glomerulosclerosis. In a study of the oligosyndactyly (Os) mutation that causes a congenital 50% reduction in nephron number, we previously found that ROP Os/+ mice developed glomerulosclerosis whereas C57B1/6J Os/+ mice did not. We concluded that the predisposition to glomerulosclerosis depended largely on the genetic background, t...
Micropuncture techniques have been used to investigate the role of each nephron segment in the river lamprey. The proximal segment reabsorbed no more than 10% of filtered water and tubular fluid here was iso-osmotic to plasma, at about 250 m-osmol. Further water reabsorption occurred in later nephron segments so that 44% °f a u filtered water was reabsorbed. Dilution of tubular fluid began in t...
The identity of niche signals necessary to maintain embryonic nephron progenitors is unclear. Here we provide evidence that Fgf20 and Fgf9, expressed in the niche, and Fgf9, secreted from the adjacent ureteric bud, are necessary and sufficient to maintain progenitor stemness. Reduction in the level of these redundant ligands in the mouse led to premature progenitor differentiation within the ni...
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