In an eleven part series published in Pathologica, we have presented various tumoral, quasitumoral and pseudotumoral lesions of the superficial and somatic soft tissue (ST), which emerged as new entities or as variants of established entities during the last quarter of a century. Detailed clinicomorphological and differential diagnostic features of approximately sixty entities were chosen on th...

Background Detection of late gadolinium enhancement (LGE) is the method of choice for imaging myocardial scar. However, patients who suffer from cardiovascular disease often are afflicted with renal impairment. As a GFR <30 ml/min bears the risk of nephrogenic systemic fibrosis it would be beneficial to develop alternative cardiac imaging methods without contrast agent. De Jong et al have alrea...

More than 72 million Americans have hypertension, and the majority of these persons have essential hypertension. However, a significant subset has a secondary cause. The most common cause of secondary hypertension is renal vascular hypertension, of which renal artery stenosis is the leading pathology. Up to 5 percent of all occurrences of hypertension are caused by renal artery stenosis, equati...

Purpose: Since the introduction of magnetic resonance imaging (MRI) in clinical routine vascular imaging always has been a challenge. Early MR angiography (MRA) techniques were based on intrinsic contrast mechanisms related to blood (non CE techniques). The development of contrast enhanced (CE) MRA techniques using gadolinium based contrast agents (GBCA) substantially changed vascular MR applic...

OBJECTIVES The aim of this work was to characterize patterns of late gadolinium enhancement (LGE) by cardiovascular magnetic resonance imaging in a hemodialysis population at high risk for cardiovascular events. BACKGROUND The prevalence and distribution of LGE and its relationship to left ventricular mass (LVM) and function in this population is unknown. METHODS Chronic hemodialysis patien...

Restrictive dermopathy (RD) is a very rare and lethal congenital skin disease. It is inherited by an autosomal recessive pattern with characteristic features of abnormally rigid skin, generalized joint contractures (arthrogryposis), and dysmorphic facies consisting of downward slanting eyes, a small pinched nose, low-set ears, a fixed open mouth in the O-position, and micrognathia. We report on...

BACKGROUND Many articles on retroperitoneal fibroses (RPFs), published over the last ten years, seem to set out as innovative the carried-out both diagnostic procedures and therapeutic measures, while a careful examination of the literature identifies them as a sheer application of previous acquisitions. Surely, instead, several interesting advances have been pointed-out in the field of pathoge...

Nephrogenic systemic fibrosis (NSF) is a fibrosing skin condition of unknown origin. Most cases have been described in patients with acute or chronic renal failure. The cutaneous changes include firm and thickened, indurate skin plaques and papules on the extremities and trunk. Histopathology typically shows an increase in dermal fibroblast-like cells associated with mucin deposition. Previous ...

Introduction: Although contrast-enhanced magnetic resonance angiography (CE-MRA) remains the technique of choice for evaluating the blood vessels of the head and neck, it is now frequently contraindicated in patients with renal insufficiency at risk for nephrogenic systemic fibrosis. Pulsed arterial spin-labeled (ASL) angiography has long been proposed as a method for unenhanced MRA [1] that ma...