Background: Acute kidney injury (AKI) is a common consequence of perinatal asphyxia, occurring in upto 56% of these neonates. It is important to recognize AKI in asphyxiated neonates to facilitate administration of appropriate fluids and electrolytes in order to improve their outcome. Objectives: To determine the incidence of AKI in asphyxiated neonates and to correlate the severity and type of...

OBJECTIVE To determine the clinical effectiveness and cost-effectiveness of testing for and empirically treating herpes simplex virus (HSV) infection in neonates with fever aged from birth to 28 days. DESIGN Cost-effectiveness analysis. SETTING Decision model. PATIENTS Neonates with fever with no other symptoms and neonates with fever with cerebrospinal fluid (CSF) pleocytosis. INTERVEN...

objective club-foot is one of the most prevalent congenital anomalies of the lowerextremities. since there is no epidemiologic study on the prevalence of thisdisease in iran, we decided to assess it in a sample population in tehran. materials and methods we assessed all neonates who were referred to the emergency department ofmofid children hospital between october 2007 and november 2008, due t...

background: to study toxoplasmosis in neonates using pcr and serological methods. methods: sera and csf of 104 neonates, hospitalized in infants' ward of taleghani hospital, tehran, iran were examined. the sera were examined for anti toxoplasma gondii lgm and lgg specific antibodies with elisa and ifa techniques, respectively. meanwhile, obtained csfs of the cases were evaluated for the genome ...

Background: Neonates affected by hereditary spherocytosis may suffer from significant jaundice. This study was conducted on neonates with jaundice hospitalized at the Children’s Hospital in Bandar Abbas, South Iran, to determine the frequency of hereditary spherocytosis among them. Patients and Methods: In this cross-sectional study, 814 neonates with jaundice hospitalized at the Children’s ...

BACKGROUND Neonates from low and middle income countries (LAMIC) tend to have lower birth weight compared with Western European (WE) neonates. Parental height, BMI and maternal parity, age and educational level often differ according to ethnic background, and are associated with offspring birth weight. Less is known about how these factors affect ethnic differences in neonatal body composition....

Background: Dyslipidemia is attributed for coronary artery diseases. Early detection of dyslipidemia in neonatal cord blood could help to identify possible future risk factors diseases new born.
 Aims and Objectives: This study was undertaken compare lipid profile small gestational age (SGA) or preterm appropriate (AGA) near-term neonates.
 Material Methods: A total 60 neonates were i...

Respiratory support improvements have aided survival of premature neonates, but infection susceptibility remains a predominant problem. We previously reported that neonatal mice have a rapidly evolving T-cell receptor (TCR) repertoire that impairs CD8+ T cell immunity. To understand the impact of prematurity on the human CD8+ TCR repertoire, we performed next-generation sequencing of the comple...

UNLABELLED Perinatal hypoxic-ischemic encephalopathy (HIE) is an important cause of brain injury in the newborn and can result devastating consequences. The principle mechanisms underlying neurological damage in HIE resulting from hypoxemia and/or ischemia is deprivation of glucose and oxygen supply which energy failure. A consequent reperfusion injury often deteriorates the brain metabolism by...

Aim: Neonates born prematurely and sick full-term neonates are at risk of brain injury. Although advances in neonatal intensive care have greatly improved the survival and outcome of these vulnerable patients, brain injury remains of major concern. Early diagnosis is important for prognostication, optimal treatment, and predicting the neurological outcome. Objective: This study was done to desc...