background: hyperbilirubinemia, or jaundice, is a life threatening disorder in newborns. it is a multifactorial disorder with many symptoms. generally, the physiological jaundice is the most prevalent type however in some regions pathological jaundice is also common. this review article focuses on a brief introduction to jaundice, its types and causes, measuring the bilirubin level, clinical ap...

Background: Neonatal jaundice is clinically presented in 60% of full-term newborns. About 8% of newborns with jaundice have urinary tract infection (UTI) without any other clinical signs in favor of UTI. In present study we evaluated clinical and paraclinical data that help to rapid and early diagnosis of UTI in apparently healthy newborns with jaundice. Methods: From February to August 2006, 5...

Optic nerve hypoplasia with hypopituitarism and intact septum pellucidum is a variant of septo-optic dysplasia or deMorsier's syndrome.' Although neonatal jaundice has been seen with this syndrome, the association with severe prolonged cholestatic jaundice has not been emphasised. We describe three patients who presented with cholestatic jaundice and were found to have optic nerve hypoplasia an...

Background: Maternal and neonatal factors could help determine the potential incidence of hyperbilirubinemia. In this study, we aimed to identify the relationship between the severity of jaundice in newborns and maternal and neonatal factors. Methods: This descriptive, cross-sectional study was conducted in 2014. Icteric newborns, admitted to Qods and Kowsar teaching hospitals in Qazvin, Iran ...

It is now well established that hyperbilirubinaemia and even kernikterus may occur in the newborn in association with glucose 6 phosphate dehydrogenase (G6PD) deficiency, in the absence of any of the other causes of neonatal jaundice (Panizon, 1960a, b; Doxiadis, Fessas, and Valaes, 1960; Doxiadis, Fessas, Valaes, and Mastrokalos, 1961; Fessas, Doxiadis, and Valaes, 1962; Smith and Vella, 1960;...

It is now well established that hyperbilirubinaemia and even kernikterus may occur in the newborn in association with glucose 6 phosphate dehydrogenase (G6PD) deficiency, in the absence of any of the other causes of neonatal jaundice (Panizon, 1960a, b; Doxiadis, Fessas, and Valaes, 1960; Doxiadis, Fessas, Valaes, and Mastrokalos, 1961; Fessas, Doxiadis, and Valaes, 1962; Smith and Vella, 1960;...

Neonatal jaundice or hyperbilirubinemia and its evolution to acute bilirubin encephalopathy (ABE) and kernicterus are an important, yet avoidable, origin of newborn deaths, re-hospitalisations and disabilities generally. In this study, a new supervised hybrid bijective soft set neural network-based classification method is introduced for prediction of Egyptian neonatal jaundice dataset. Early p...

After completing this article, readers should be able to: 1. List the risk factors for severe hyperbilirubinemia. 2. Distinguish between physiologic jaundice and pathologic jaundice of the newborn. 3. Recognize the clinical manifestations of acute bilirubin encephalopathy and the permanent clinical sequelae of kernicterus.4. Describe the evaluation of hyperbilirubinemia from birth through 3 mon...

In a Chinese population 1,000 full-term male neonates and a further 117 jaundiced neonates of both sexes were studied in an investigation of the frequency of deficiency of erythrocyte glucose-6-phosphate dehydrogenase (G6PD). This enzyme was found to be deficient in 3.6% of male neonates. Correlation of the results with the birthplace of the 602 mothers who were known to come from Kwangtung pro...