Berry PJ, Nagington J. Fatal infection with echovirus 11. Arch Dis Child 1982;57:22-9. 2 Krous HF, Dietzman D, Ray CG. Fatal infection with echovirus types 6 and 11 in early infancy. Am J Dis Child 1973;126:842-6. 3 Hughes JR, Wilfert CM, Moore M, et al. Echovirus 14 infection associated with fatal neonatal hepatic necrosis. Am J Dis Child 1972;123:61-7. 4 Philip AGS, Larson EJ. Overwhelming ne...

Background: Neonatal mortality remains a public health concern in developing countries such as Burkina Faso. Improving the survival rate of newborns requires a good knowledge of the current situation. This study aimed at determining the risk factors for neonatal mortality in the Neonatology Department of Saint Camille Hospital of Ouagadougou (HOSCO - Hôpital Saint ...

Maternal colonization with group B Streptococcus (GBS) during pregnancy increases the risk of neonatal infection by vertical transmission. However, it remains unclear whether treating all colonized women during labor exposes a large number of their neonates to possible adverse effects without benefit. We performed a meta-analysis to assess the effect of intrapartum antibiotic prophylaxis on neo...

Severe respiratory viral infection in early life is associated with recurrent wheeze and asthma in later childhood. Neonatal immune responses tend to be skewed toward T helper 2 (Th2) responses, which may contribute to the development of a pathogenic recall response to respiratory infection. Since neonatal Th2 skewing can be modified by stimulation with Toll-like receptor (TLR) ligands, we inve...

Both human and murine neonates are characteristically highly susceptible to bacterial infections. However, we recently discovered that neonatal mice are surprisingly highly resistant to oral infection with Yersinia enterocolitica. This resistance was linked with activation of both innate and adaptive responses, involving innate phagocytes, CD4+ cells, and B cells. We have now extended these stu...

BACKGROUND Canid herpesvirus-1 (CaHV-1) infection in puppies less than three weeks of age is often reported to be associated with a lethal generalized necrotizing inflammation and since the discovery of the virus in 1965 several reports of neonatal infections have been published. However, the significance of CaHV-1 for peri- and neonatal mortality in puppies remains unclear. Therefore, we exami...

Objective: This paper presents specific pregnancy outcomes of COVID-19 during pregnancy, based on the literature available until August 2020. Methods: A systematic review was conducted in PubMed, Scopus, Google Scholar, Springer, Science Direct, and EMBASE database publications regarding coronavirus disease (COVID-19) following PRISMA checklist. The search terms used include: “pregnancy”; “preg...

Infection and sepsis remain among the leading causes of neonatal mortality. The susceptibility newborns to infection can be attributed their immature immune system. Regarding response, monocytes represent a numerically minor population leukocytes. However, they contribute variety immunological demands, such as continuous replenishment resident macrophages under non-infectious conditions migrati...

Neonatal sepsis is a life-threatening disease. Early diagnosis essential, but no single marker of infection has been identified. Sepsis activates coagulation cascade with simultaneous production the D-dimers due to lysis fibrin. D-dimer test reflects activation system.

CONTEXT Neonatal infections are frequent complications of extremely low-birth-weight (ELBW) infants receiving intensive care. OBJECTIVE To determine if neonatal infections in ELBW infants are associated with increased risks of adverse neurodevelopmental and growth sequelae in early childhood. DESIGN, SETTING, AND PARTICIPANTS Infants weighing 401 to 1000 g at birth (born in 1993-2001) were ...