Introduction The neonatal period is a highly vulnerable time for an infant completing many of the physiologic adjustments required for life outside the uterus. As a result, there are high rates of morbidity and mortality. The three major causes of mortality in developing countries include prematurity, infection, and perinatal asphyxia. The aim of this study was to identify the patterns of neona...

Purpose: The use of therapeutic hypothermia (TH) has increased in the treatment of comatose victims of cardiac arrest, traumatic brain injury, refractory dysrhythmias, neonatal encephalopathy and asphyxia, near-drowning and hemorrhagic shock. The purpose of this study was to ascertain the level of understanding of TH use for comatose victims of cardiac arrest among healthcare providers in two d...

INTRODUCTION Hypothermia is a major factor associated with neonatal mortality in low and middle income countries. Thermal care protection of newborn through a series of measures taken at birth and during the initial days of life is recommended to reduce the hypothermia and associated neonatal mortality. This study aimed to identify the prevalence of and the factors associated with receiving 'op...

OBJECTIVE To assess the feasibility and safety of cooling asphyxiated neonates using phase changing material based device across different neonatal intensive care units in India. DESIGN Multi-centric uncontrolled clinical trial. SETTING 11 level 3 neonatal units in India from November 2014 to December 2015. PARTICIPANTS 103 newborn infants with perinatal asphyxia, satisfying pre-defined c...

BACKGROUND Cerebral hypothermia can improve outcome of experimental perinatal hypoxia-ischaemia. We did a multicentre randomised controlled trial to find out if delayed head cooling can improve neurodevelopmental outcome in babies with neonatal encephalopathy. METHODS 234 term infants with moderate to severe neonatal encephalopathy and abnormal amplitude integrated electroencephalography (aEE...

Abstract Background Neonatal hypoxic-ischemic encephalopathy (HIE) affects as many 100,000 infants each year in China. Therapeutic hypothermia reduces HIE related mortality and long-term neurodevelopmental disabilities. National guidelines for management were published a decade ago. This study aimed to investigate the current status of diagnosis treatment Method prospective cross-sectional nati...

Hypothermia is associated with large number of serious complications. We face a lot of problems while treating babies with preoperative and post operative hypothermia. Hypothermia is preventable if proper measures are taken. In our set up we do not have proper warming system in neonatology units. We managed hypothermia successfully in neonates preoperatively and post-operatively with the help o...

Mortality in piglets during the perinatal period, especially first days after birth, is frequently caused by non-infectious conditions, such as hypoglucemia or low birth weight, which can be associated with hypothermia experienced at birth. The thermal stability of newborn a fundamental aspect neonatal care, so maintaining constant, ideal temperature will substantially reduce mortality. Species...

BACKGROUND Some inhalation anesthetics increase apoptotic cell death in the developing brain. Xenon, an inhalation anesthetic, increases neuroprotection when combined with therapeutic hypothermia after hypoxic-ischemic brain injury in newborn animals. The authors, therefore, examined whether there was any neuroapoptotic effect of breathing 50% xenon with continuous fentanyl sedation for 24 h at...