Introduction: During the neonatal period, metabolism of bilirubin is in transition from the fetal stage to the adult stage1. Uridine diphosphoglucuronyl transferase (UDPGT), an important liver enzyme for conjugation and excretion of bilirubin, is detectable at 18 – 20 weeks of gestation. UDPGT levels in full term neonates are usually less than 0.1% of adult values. Adult value of this enzyme ac...

Background: Low antioxidant system may contribute to the severity of neonatal hyperbilirubinemia. Aim work: This study was performed clarify relationship between serum   25-hydroxyvitamin-D (25[OH] D) and hyperbilirubinemia in full-term neonates. Methods: This is a cross sectional case control with aim determining whether there an association serum indirect bilirubin vitamin D levels newborns j...

Jaundice (also known as hyperbilirubinemia) is a yellowish-greenish pigmentation of the sclera and skin caused by an increase in bilirubin production or a defect in bilirubin elimination. Management of hyperbilirubinemia is one of the most common reasons for readmission of a newborn. Prolonged unconjugated hyperbilirubinemia can result in acute bilirubin encephalopathy and eventually develop in...