The author acknowledges his indebtedness to the teachings of Fournier on syphilis, and to that of Finger and Neisser on gonorrhoea. Dr. Marshall also emphasizes the importance of both syphilis and gonorrhoea, " the oldest diseases which afflict mankind," as etiological factors in disease. The historical chapter is very interesting. It is clearly shown that syphilis was well known before the gre...

This paper deals with an investigation of the effect of these reactions on bacteria. Not only the common staining behavior but also certain other similarities (Fischer et al., 1949; Fischer, 1951) between intact wool and gram negative bacteria, medium degraded wool and gram variable bacteria, as well as between highly degraded wool and gram positive bacteria suggested that reversal of gram stai...

The Congo red stain has undergone several modifications since it was first used by Bennhold in 1922 in order to increase the specificity for staining amyloid. Most of the laboratories in the United States use the method of Puchtler which uses alkaline Congo red solution. Some of the variables associated with the procedure were investigated by us. Our results showed the following: (1) amyloid sh...

Pathological diagnosis relies on the visual inspection of histologically stained thin tissue specimens, where different types stains are applied to bring contrast and highlight various desired histological features. However, destructive histochemical staining procedures usually irreversible, making it very difficult obtain multiple same section. Here, we demonstrate a virtual stain transfer fra...

Pathology is practiced by visual inspection of histochemically stained slides. Most commonly, the hematoxylin and eosin (H&E) stain used in diagnostic workflow it gold standard for cancer diagnosis. However, many cases, especially non-neoplastic diseases, additional "special stains" are to provide different levels contrast color tissue components allow pathologists get a clearer picture. In thi...