نتایج جستجو برای: natural regulatory t cells
تعداد نتایج: 2435484 فیلتر نتایج به سال:
The organization of the thymus into distinct cortical and medullary regions enables it to control the step-wise migration and development of immature T-cell precursors. Such a process provides access to specialized cortical and medullary thymic epithelial cells at defined stages of maturation, ensuring the generation of self-tolerant and MHC-restricted conventional CD4(+) and CD8(+) αβ T cells....
BACKGROUND AND OBJECTIVES Cell-based therapy with natural (CD4(+)CD25(hi)CD127(lo)) regulatory T cells to induce transplant tolerance is now technically feasible. However, regulatory T cells from hemodialysis patients awaiting transplantation may be functionally/numerically defective. Human regulatory T cells are also heterogeneous, and some are able to convert to proinflammatory Th17 cells. Th...
htlv-1 is the causative agent for a neurologic disease named htlv-i- associated myelopathy/tropical spastic paraparesis (ham/tsp). paraparesis of the lower limbs which appears gradually is the most common clinical feature of this disease. it has been shown that the indirect involvement of the nervous system by lymphocytes is more probable than the direct attack of the virus to the neurons. htlv...
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