نتایج جستجو برای: natural hydrogel

تعداد نتایج: 494046  

2011
HN Lim NM Huang SS Lim I Harrison CH Chia

BACKGROUND Three-dimensional assembly of graphene hydrogel is rapidly attracting the interest of researchers because of its wide range of applications in energy storage, electronics, electrochemistry, and waste water treatment. Information on the use of graphene hydrogel for biological purposes is lacking, so we conducted a preliminary study to determine the suitability of graphene hydrogel as ...

2017
Xiaoli Wu Liumin He Wen Li Heng Li Wai-Man Wong Seeram Ramakrishna Wutian Wu

Peripheral nerves are fragile and easily damaged, usually resulting in nervous tissue loss, motor and sensory function loss. Advances in neuroscience and engineering have been significantly contributing to bridge the damage nerve and create permissive environment for axonal regrowth across lesions. We have successfully designed two self-assembling peptides by modifying RADA 16-I with two functi...

Journal: :Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2015
Yong-Beom Park Minjung Song Choong-Hee Lee Jin-A Kim Chul-Won Ha

This study was carried out to assess the feasibility of human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) in articular cartilage repair and to further determine a suitable delivering hydrogel in a rat model. Critical sized full thickness cartilage defects were created. The hUCB-MSCs and three different hydrogel composites (hydrogel A; 4% hyaluronic acid/30% pluronic (1:1, v/...

Journal: :Journal of biomedical materials research. Part B, Applied biomaterials 2011
Rozaini Mohd Zohdi Zuki Abu Bakar Zakaria Norimah Yusof Noordin Mohamed Mustapha Muhammad Nazrul Hakim Abdullah

Malaysian sea cucumber was incorporated into hydrogel formulation by using electron beam irradiation technique and was introduced as novel cross-linked Gamat Hydrogel dressing. This study investigated whether Gamat Hydrogel enhanced repair of deep partial skin thickness burn wound in rats and its possible mechanism. Wounds were treated with either Gamat Hydrogel, control hydrogel, OpSite® film ...

2017
Georgia Kaklamani David Cheneler Liam M Grover Michael J Adams Spiros H Anastasiadis James Bowen

Efforts to develop tissue-engineered skin for regenerative medicine have explored natural, synthetic, and hybrid hydrogels. The creation of a bilayer material, with the stratification exhibited by native skin, is a complex problem. The mechanically robust, waterproof epidermis presents the stratum corneum at the tissue/air interface, which confers many of these protective properties. In this wo...

Journal: :Biomaterials 2011
Yuguo Lei Shiva Gojgini Jonathan Lam Tatiana Segura

Synthetic hydrogel scaffolds that can be used as culture systems that mimic the natural stem cell niche are of increased importance for stem cell biology and regenerative medicine. These artificial niches can be utilized to control the stem cell fate and will have potential applications for expanding/differentiating stem cells in vitro, delivering stem cells in vivo, as well as making tissue co...

2015
Lewis A. Reis Loraine L. Y. Chiu Jun Wu Nicole Feric Carol Laschinger Abdul Momen Ren-Ke Li

Background—Hydrogels are being actively investigated for direct delivery of cells or bioactive molecules to the heart post-myocardial infarction (MI) to prevent cardiac functional loss. We postulate that immobilization of the pro-survival angiopoietin-1-derived peptide, QHREDGS, to a chitosan-collagen hydrogel could produce a clinically translatable thermo-responsive hydrogel to attenuate post-...

2012
Caner Nazli Tugba Ipek Ergenc Yasemin Yar Havva Yagci Acar Seda Kizilel

The objective of this study was to develop thin, biocompatible, and biofunctional hydrogel-coated small-sized nanoparticles that exhibit favorable stability, viability, and specific cellular uptake. This article reports the coating of magnetic iron oxide nanoparticles (MIONPs) with covalently cross-linked biofunctional polyethylene glycol (PEG) hydrogel. Silanized MIONPs were derivatized with e...

2014
P Humbert B Faivre Y Véran C Debure F Truchetet P-A Bécherel P Plantin J-C Kerihuel SA Eming J Dissemond G Weyandt D Kaspar H Smola P Zöllner

BACKGROUND Stringent control of proteolytic activity represents a major therapeutic approach for wound-bed preparation. OBJECTIVES We tested whether a protease-modulating polyacrylate- (PA-) containing hydrogel resulted in a more efficient wound-bed preparation of venous leg ulcers when compared to an amorphous hydrogel without known protease-modulating properties. METHODS Patients were ran...

2015
SZE LIM ISHAK AHMAD AZWAN MAT LAZIM

The purpose of this study was to produce a novel pH sensitive hydrogel with superior thermal stability, composed of poly(acrylic acid) (PAA) and cellulose nanocrystal (CNC). CNC was extracted from kenaf fiber through a series of alkali and bleaching treatments followed by acid hydrolysis. PAA was then subjected to chemical cross-linking using the crosslinking agent (N,N-methylenebisacrylamide) ...

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