BACKGROUND & OBJECTIVES Leishmaniasis has an annual incidence of 0.5-1.5 million new cases and is endemic in 88 countries throughout the world. About 90% of cases of cutaneous leishmaniasis (CL) are reported from seven countries including Iran. Evidence suggests the increased annual incidence of this disease in Iran. Intracellular protozoan parasite, Leishmania, is an obligatory parasite. Sandf...

INTRODUCTION Mitochondrial acetoacetyl-CoA thiolase (3-oxothiolase) deficiency is a rare metabolic disorder involving ketone body metabolism characterized by acute attacks of vomiting, acidosis, ketosis, and lethargy along with some laboratory criteria including excessive excretion of 2-methyl-3-hydroxybutyric acid in urine. CASE PRESENTATION This is a case report of 3-oxothiolase deficiency ...

Deficiencies of coagulation factors other than factor VIII and factor IX that cause bleeding disorders are inherited as autosomal recessive traits and are rare, with prevalences in the general population varying between 1 in 500 000 and 1 in 2 million for the homozygous forms. As a consequence of the rarity of these deficiencies, the type and severity of bleeding symptoms, the underlying molecu...

After having coordinated their nationality laws since the late 19th century, the Scandinavian countries have moved in distinctly different directions in this field since the turn of the millennium. Today Sweden has one of the most liberal citizenship policies in Europe, while Denmark has one of the most restrictive. Norway occupies an intermediate position between its Scandinavian neighbours. I...

Marriages among the Sikh minority of the Districts of Swat, Bunair and Shangla (NWFP, Pakistan) were studied where the frequency of consanguineous marriages was found to be 21%. Marriages with distant relatives were 29.4% in the population. The inbreeding coefficient for the population was calculated to be 0.0127. Only three types of first cousin marriages (MSD, MBD and FSD) were recorded. Marr...

BACKGROUND Hepatitis C Virus (HCV) infection is one of the most important causes of chronic liver disease and related problems in the world .There are few population-based studies on the prevalence and risk factors of hepatitis C infection in Iran, which could not provide enough information. Moreover, the prevalence and risk factors of hepatitis C infection are not similar in all parts of Iran....