OBJECTIVE After radical retropubic prostatectomy a rise of the prostate-specific antigen (PSA) indicates a local recurrent or metastatic disease. If the bone scan shows no apparent bone metastasis, morphological imaging methods like x-ray computed tomography, magnetic resonance imaging or transrectal ultrasound often cannot distinguish between postoperative scar and local recurrence. Therefore ...

introduction: breast cancer is the most common cancer in women worldwide and her-2 is one importantly prognostic factor in this cancer. tumor markers use as a criterion for predicting recurrence, but in breast cancer physical examination and mammography are important factors that are recommended for following up the recurrence. the aim of this study was to assess the correlation between breast ...

Background: Tumor-specific growth factor (TSGF) is associated with invasion and metastasis of various malignancies adverse clinical outcomes. TSGF also highly expressed in cervical cancer (CC), but its value unclear. Materials Methods: Serum samples from malignancies, including CC, non-Hodgkin’s lymphoma (NHL), nasopharyngeal carcinoma (NPC), colorectal (CRC), lung (LCA), ovarian (OC), breast (...

PURPOSE To find molecular markers from expression profiling data to predict recurrence of laryngeal cancer after radiotherapy. EXPERIMENTAL DESIGN We generated gene expression data on pre-treatment biopsies from 52 larynx cancer patients. Patients developing a local recurrence were matched for T-stage, subsite, treatment, gender and age with non-recurrence patients. Candidate genes were then ...

Recurrence or metastasis of cancer has been considered to occur in the last stage of the patient's life. However, the new notions of oligometastases and oligo-recurrence have been proposed and the paradigm shift in the conceptualization of cancer metastasis or cancer recurrence. Oligometastases is the state in which the patient shows distant relapse in only a limited number of regions. Local th...

Rectal cancer accounts for 5% of all deaths from cancer, and 1 0,000 new cases present each year. The overall five-year survival is 31 % and one of the most distressing forms of recurrence after surgery is local recurrence. What is surprising about this local recurrence is that it varies from surgeon to surgeon by from 5 to 35%.1 There is also the suspicion that with the introduction of staplin...

Introduction: In the surgical management of juvenile nasopharyngeal angiofibromas the possibility of recurrences and residual tumours is always there. This study was undertaken to predict the prognostic factors determining recurrence of juvenile nasopharyngeal angiofibroma and to find out the usual sites

OBJECTIVE Resection is the best treatment for patients with stage I non-small cell lung cancer (NSCLC). Patterns of disease recurrence after complete resection in stage I NSCLC have not been well demonstrated. The aim of this study was to evaluate the prognostic predictors of post-recurrence survival in patients with resected stage I NSCLC with local recurrence. METHODS The clinicopathologica...

background : magnetic resonance imaging of the breast is becoming a useful adjunct to mammography and sonography for the detection of breast lesions. however, it is not yet accepted as a routine examination for all breast cancer patients due to the lack of data regarding whether breast magnetic resonance imaging impacts recurrence or survival. this trial examines the use of magnetic resonance i...

OBJECTIVE Patients with nasopharyngeal carcinoma experience highly variable outcomes despite receiving similar therapeutic regimens. Identifying biomarkers that predict survival and guide individualized therapy is urgently needed. Cystatin C has been explored as a valuable prognostic marker in several malignancies. We retrospectively assessed the relationship between serum cystatin C levels and...