A 69 year-old man, with bilateral inflamed sinonasal polyps that had been treated medically for years, referred for surgical treatment suffering from moderate progressive bilateral nasal obstruction, sinus pressure with no rhinorrhoea or other symptoms and typical bilateral inflamed polyps emerging from the middle meatus, not exceeding the level of the lower concha (Endoscopic Appearance Score ...

A 69 year-old man, with bilateral inflamed sinonasal polyps that had been treated medically for years, referred for surgical treatment suffering from moderate progressive bilateral nasal obstruction, sinus pressure with no rhinorrhoea or other symptoms and typical bilateral inflamed polyps emerging from the middle meatus, not exceeding the level of the lower concha (Endoscopic Appearance Score ...

BACKGROUND/AIM The aim of this study was to investigate the etiological role of human papilloma virus (HPV), herpes simplex virus (HSV), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), and human herpes virus-6 (HHV-6) and -7 (HHV-7) in the occurrence of nasal polyposis. MATERIALS AND METHODS Nasal polyp samples from 30 patients with nasal polyposis and normal na...

BACKGROUND : Accumulation of T cells and immature dendritic cells (DCs) is one of the characteristic features of nasal polyps. However, the question remains why these cells accumulate in nasal polyp tissue. Macrophage inflammatory protein-3α; (MIP-3α;/CCL20) is a chemokine involved in the migration of T cells and immature DCs into inflammatory tissue sites. Fibroblasts are a rich source of cyto...

BACKGROUND The waiting time for functional endoscopic sinus surgery (FESS) in patients with chronic rhinosinusitis with nasal polyposis (CRSwNP) in the Canadian public healthcare system can be lengthy. Many such patients have significant nasal obstruction resulting in a poor quality of life. A simple and safe office-based polypectomy device to debulk nasal polyps allows immediate alleviation of...

Method Patients with nasal polyps were recruited from the clinic, adult first-degree relatives of the patients were asked to participate. Our intention was to recruit one relative of each gender per patient. All participants were examined with nasal endoscopy and underwent a structured interview regarding upper airway symptoms and risk factors. The results were compared with a general populatio...

UNLABELLED The nasal polyps associated with Samter's triad are often very extensive, difficult to treat, with great tendency to recurrence. In this paper the current opinion on nasal polyps management in aspirin triad patients was presented. PATHOGENESIS Opinions on pathogenesis of these disease was remembered as well as its epidemiology. DIAGNOSTIC METHODS The available diagnostic methods ...

UNLABELLED Chronic rhinosinusitis' pathogenesis is not completely established and there are some explanations for this disease, such as osteitis, superantigens, fungal-mediated hypersensitivity and, more recently, biofilms. There are no reports in Portuguese about biofilms in chronic rhinosinusitis. AIM To reproduce a method for visualization of biofilms in patients with chronic rhinosinusiti...