BACKGROUND Psoriasis is associated with a systemic inflammation and an increased frequency of the metabolic syndrome, both of which are believed to link psoriasis to an increased risk of cardiovascular disease. OBJECTIVE The study aimed to investigate the systemic expression of markers of cardiovascular risk and determine their response to ultraviolet B therapy and treatment with the tumor ne...

Narrowband ultraviolet-B (NB-UVB) phototherapy is the mainstay of vitiligo therapy. The response can be evaluated using area scoring index (VASI) and repigmentation grade. However, few studies used VASI to evaluate there are no definitive data on reduction VASI. This retrospective descriptive study aimed determine characteristics decrease in patients with after 36 48 sessions NB-UVB phototherap...

Primary cutaneous lymphomas (PCLs) are exceedingly rare in children and adolescents, with mycosis fungoides (MF) being the most frequent PCL diagnosed childhood. There numerous unusual clinical variants of MF, including hypopigmented type form (HMF). HMF is exceptional overall, but comparatively common among children. We present an 8-year-old boy a 3-year history progressive, generalised, scaly...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : lichen planus is recognized as an inflammatory disease of the skin with different morphologic patterns. different treatment modalities, including topical and systemic corticosteroids, methotrexate, cyclosporine, azathioprine, topical calcineurin inhibitors, and psoralen  plus uva ( puva), have been suggested f...

This detailed and user-friendly guideline for the diagnosis and management of vitiligo in children and adults aims to give high quality clinical advice, based on the best available evidence and expert consensus, taking into account patient choice and clinical expertise. The guideline was devised by a structured process and is intended for use by dermatologists and as a resource for interested p...

Vitiligo is a common, acquired pigmentary disorder of unknown pathogenesis that presents a therapeutic challenge to many dermatologists (Figure 1). Although surgery in the form of grafting or transplantation is generally the most definitive treatment option, these procedures are limited by concerns of post-procedure cosmesis. Photochemotherapy using psoralen and ultraviolet A (PUVA) therapy, to...

BACKGROUND Pityriasis lichenoides (PL)-like skin lesions rarely appear as a specific manifestation of mycosis fungoides (MF). OBJECTIVE We investigated the clinicopathological features, immunophenotypes, and treatments of PL-like MF. METHODS This study included 15 patients with PL-like lesions selected from a population of 316 patients diagnosed with MF at one institution. RESULTS The pat...

INTRODUCTION Extracts of the tropical fern Polypodium leucotomos appear to possess beneficial properties for the skin attributed to the presence of numerous compounds within the extract that have antioxidant and photoprotective properties. Orally administered Polypodium leucotomos may provide protection against the detrimental photoaging effects of sunlight and can also help reduce the frequenc...