The large scale patterning of therapeutic proteins is a key to the efficient design, characterization, and production of biologics for cost effective, high throughput, and point-of-care detection and analysis system. We demonstrate an efficient method for protein deposition and adsorption on nanoporous silica substrates in specific patterns using a method called ‘‘micro-contact printing’’. Mult...

Several synthesis routes have been developed and correlations between the variables of procedure physicochemical properties nanoporous silica materials MCM-48 type deposited by template method in presence a low-valent iron (II) cation investigated. Changes structure mesoporous framework, its textural degree energy inhomogeneity surface were studied depending on Fe/Si molar ratio, pH values (4 9...

This article reports on a molecular simulation study of nitrogen adsorption and condensation at 77 K in atomistic silica cylindrical nanopores (MCM-41). Two models are considered for the nitrogen molecule and its interaction with the silica substrate. In the "pea" model, the nitrogen molecule is described as a single Lennard-Jones sphere and only Lennard-Jones interactions between the nitrogen ...

Magnolol (MG) is a small-molecule neolignan polyphenolic compound isolated from the genus Magnolia. The anti-inflammatory, anti-oxidative, anti-diabetic, anti-tumorgenic, anti-neurodegenerative, anti-depressant and anti-microbial properties of MG are well documented in recent literature. These fascinating multiple biological activities of MG encourage research about the development of new deliv...

The entrapment of nanolipoprotein particles (NLPs) and liposomes in transparent, nanoporous silica gel derived from the precursor tetramethylorthosilicate was investigated. NLPs are discoidal patches of lipid bilayer that are belted by amphiphilic scaffold proteins and have an average thickness of 5 nm. The NLPs in this work had a diameter of roughly 15 nm and utilized membrane scaffold protein...