Background. Chronic renal insufficiency is associated with the retention of solutes normally excreted by healthy kidneys. P-cresol, a prototype protein-bound uraemic retention solute, has been shown to exert toxic effects in vitro. Recently, however, it has been demonstrated that p-cresol in the human body is conjugated, with p-cresylsulphate as the main metabolite. Methods. The present study e...

BACKGROUND Chronic renal insufficiency is associated with the retention of solutes normally excreted by healthy kidneys. P-cresol, a prototype protein-bound uraemic retention solute, has been shown to exert toxic effects in vitro. Recently, however, it has been demonstrated that p-cresol in the human body is conjugated, with p-cresylsulphate as the main metabolite. METHODS The present study e...

Stool specimens examined for the presence of Clostridium difficile and its cytotoxin were screened by gas liquid chromatography for the presence of volatile fatty acids and p-cresol. Twenty seven of 110 (25%) stools yielded C difficile or cytotoxin; iso-valeric acid was detected in 63/110 (57%) and iso-caproic acid in 18/110 (16%) stools. Para-cresol was found in 24/71 (34%) stools examined. Is...

Control of intermolecular interactions is crucial to the exploitation of molecular semiconductors for both organic electronics and the viable manipulation and incorporation of single molecules into nano-engineered devices. Here we explore the properties of a class of materials that are engineered at a supramolecular level by threading a conjugated macromolecule, such as poly(para-phenylene), po...

Tissue engineering is used for regenerating bioartificial tissues using suitable cells and biocompatible scaffold materials. The present study aims to prepare poly (lactic acid) (PLA) nanoparticles as an extracellular matrix use in bone tissue engineering. For this purpose, the stem originating from human umbilical cord were extracted their adhesion, growth, osteoblastic differentiation on PLA ...

We examined the anaerobic degradation of phenol and the ortho, meta, and para isomers of chlorophenol, methoxyphenol, methylphenol (cresol), and nitrophenol in anaerobic sewage sludge diluted to 10% in a mineral salts medium. Of the 12 monosubstituted phenols studied, only p-chlorophenol and o-cresol were not significantly degraded during an 8-week incubation period. The phenol compounds degrad...

interactions of cationic tetrakis (n,n´,n´´,n´´´-tetramethyltetra-3,4-pyridinoporphyrazinatocobalt(ii) (co(tmtppa)) with synthetic polynucleotides, poly(a-t), poly(g-c) and calf thymus dna have been characterized in 5 mm phosphate buffer, ph 7.2, by optical absorption and fluorescence spectroscopy. the appearance of hypochromicity effect and the red shift in uv-vis spectrum of porphyrazine was ...

BACKGROUND Several studies have pointed to a release of drugs or protein-bound solutes from their binding sites during heparinization. The effect is attributed to the metabolism of triglycerides to free fatty acids (FFAs), which compete with drugs for protein binding sites. This study evaluated the impact of intradialytic heparin on the free concentration of the uremic toxin p-cresol and on FFA...

Common bean (Phaseolus vulgaris L.) is one of the most important and widely cultivated Legume in the world. The two-spotted spider mite (TTSM), is one of the most important agricultural pests. This research provided some evidence of the applicability of CuO nano particles and nano capsule for controlling TTSM. To evaluate the effect of copper nano-capsules on the populations of TSSM from red be...

In this work, we prepare and characterize multiphasic thin films containing poly(?-caprolactone), PCL, poly(butylene succinate), PBS, a poly (butylene succinate-ran-?-caprolactone) (PBS-ran-PCL) random copolyester. To that aim, were prepared by sequential dipping of silicon substrate into chloroform solutions the respective polymers. The preparation method resulted in with varying compositions ...