The purpose of this study was to assess the effectiveness activated nano-curcumin as a cancer-targeted therapy. Six groups albino mice with cancer implants were used for study. Sono- (ultrasound) and photo- (blue laser) energy sources. outcomes showed that is an effective photo-sono sensitizer treatment cancer. Upon activation blue laser and/or ultrasound, plays crucial part in inhibiting tumor...

Tamoxifen is routinely used for treatment of Estrogen-positive breast carcinoma. Approximately, 50% of patients with metastatic cancer will develop resistance to Tamoxifen. In this research, Tamoxifen was combined with the anti-cancer compound Curcumin. Diblock nanopolymer was used to package the new formulation of Curcumin and Tamoxifen. Anti-cancer efficacy of the obtained compound was evalua...

Objective: Thepurpose of this study was to investigate the effect of 6 weeks of HIIT training combining nano-curcumin supplement on antioxidant defense and lipid degradation in overweight girls. Materials and Methods: The research method was semi-experimental study. Accordingly, 48 overweight girl students were randomly divided into four groups: training (n=12), training-supplement (n=12), sup...

Tamoxifen is routinely used for treatment of Estrogen-positive breast carcinoma. Approximately, 50% of patients with metastatic cancer will develop resistance to Tamoxifen. In this research, Tamoxifen was combined with the anti-cancer compound Curcumin. Diblock nanopolymer was used to package the new formulation of Curcumin and Tamoxifen. Anti-cancer efficacy of the obtained compound was evalua...

In this study 152 bacterial strains were isolated from the contaminated oils in the southwest of Iran. Hemolysis was used as a criterion for the primary  isolation of biosurfactant producing-bacteria. Fifty five strains had haemolytic activity , among them tweleve strains were good biosurfactant producers by measuring surface tension and emulsification activity.Two microorganism showe...

Novel amphiphilic poly-N-vinylpyrrolidone derivatives with different molecular weight of hydrophilic PVP fragment and one secondary di-n-alkyl terminal hydrophobic fragment of different length were synthesized to compare their inclination for formation of nano-scaled micelle-like aggregates in aqueous media with previously studied primary n-alkyl terminated poly-N-vinylpyrrolidones. The behavio...

Cellulose is a prominent scaffolding polysaccharide found in plants as micro fibrils which form the structurally strong framework cell walls. It has wide variety of uses such attacking agent, emulsifier, stabilizer etc. Its use can be further enhanced by converting cellulose into derivatives. One most important derivatives carboxy methyl (CMC). In present study, converted to CMC thereby prepari...

Unimolecular polymeric micelles have several features, such as thermodynamic stability, small particle size, biocompatibility, and the ability to internalize hydrophobic molecules. These micelles have recently attracted significant attention in various applications, such as nano-reactors, catalysis, and drug delivery. However, few attempts have explored the formation mechanisms and conditions o...

BACKGROUND AND METHODS Curcumin has extraordinary anticancer properties but has limited use due to its insolubility in water and instability, which leads to low systemic bioavailability. We have developed a novel nanoparticulate formulation of curcumin encapsulated in stearic acid-g-chitosan oligosaccharide (CSO-SA) polymeric micelles to overcome these hurdles. RESULTS The synthesized CSO-SA ...