نتایج جستجو برای: naloxone 5mgkg

تعداد نتایج: 4628  

Journal: :American journal of public health 2015
Mark Faul Michael W Dailey David E Sugerman Scott M Sasser Benjamin Levy Len J Paulozzi

OBJECTIVES We determined the factors that affect naloxone (Narcan) administration in drug overdoses, including the certification level of emergency medical technicians (EMTs). METHODS In 2012, 42 states contributed all or a portion of their ambulatory data to the National Emergency Medical Services Information System. We used a logistic regression model to measure the association between nalo...

Journal: :تحقیقات دامپزشکی 0
اسماعیل تمدنفرد گروه علوم پایه دانشکده دامپزشکی دانشگاه ارومیه مجتبی گلی دانش آموخته دانشکده دامپزشکی دانشگاه ارومیه صونا سیدنژاد کارشناس آزمایشگاه فیزیولوژی دانشکده دامپزشکی دانشگاه ارومیه

effects of insulin (1, 2 and 3 iu/kg, i.p.), morphine (5mg/kg, i.p.), naloxone (5mg/kg, s.c.), insulin before morphine and after naloxone were studied in the formalin test of mice. formalin test was induced by intraplantar injection of formalin (20m, 5%). morphine alone and insulin with morphine decreased the first phase (0-5 min) of pain. naloxone increased the interphase (6-20 min) of nicicep...

Journal: :Stroke 1984
R J Fallis M Fisher R A Lobo

Naloxone has been reported to have potential benefit in the treatment of stroke. We evaluated the effect of naloxone in a double-blind trial conducted with 15 stroke patients whose deficits ranged from 8 to 60 hours in duration. All but one patient sustained a cerebral infarction. Neurologic function was assessed before and five minutes after each of two injections given to each patient in a do...

2013
Ingunn O. Lund Gabriele Fischer Gabrielle K. Welle-Strand Kevin E. O’Grady Kimber Debelak William R. Morrone Hendrée E. Jones

Given that buprenorphine + naloxone is prescribed for opioid-dependent pregnant women, it is important to examine the extent to which it differs from buprenorphine alone, methadone, or methadone-assisted withdrawal on neonatal and maternal outcomes. Summary statistics on maternal and neonatal outcomes were collected from 7 previously published studies examining treatment for opioid-dependent pr...

Journal: :Behavioral neuroscience 2000
G P McNally I N Johnston R F Westbrook

We used the tail-flick response of rats to study the role of opioid receptors in illness-induced hyperalgesia. An intraperitoneal injection of lithium chloride (LiCl) produced hyperalgesia that was blocked in a dose-dependent manner by subcutaneous injection of the opioid antagonist naloxone. Neither hyperalgesia nor its blockade by naloxone were due to variations in tail-skin temperature induc...

Journal: :British medical journal 1976
J M Evans M I Hogg M Rosen

Naloxone 40 mug was administered intravenously one minute after birth to 20 out of 44 neonates whose mother had been given pethidine in labour. These neonates were compared with 20 others whose mothers had had only lumbar epidural block. Alveolar PCO2, alveolar ventilation, and ventilatory rate were measured 10 and 30 minutes after birth. The untreated neonates of mothers who had had pethidine ...

Journal: :Pain 2000
W Meissner U Schmidt M Hartmann R Kath K Reinhart

Opioid-related constipation is one of the most frequent side effects of chronic pain treatment. Enteral administration of naloxone blocks opioid action at the intestinal receptor level but has low systemic bioavailability due to marked hepatic first-pass metabolism. The aim of this study was to examine the effects of oral naloxone on opioid-associated constipation in an intraindividually contro...

2015
Erin L Winstanley Angela K Clark Judith Feinberg

Drug overdose is now the leading cause of injury death in the United States, surpassing deaths from motor vehicle accidents in 2008 [1]. Naloxone, a short-acting mu opioid receptor antagonist, can reverse an opioid overdose and prevent fatality [2]. Opioid overdose prevention programs (OOPPs) provide education on overdose prevention and some have begun to distribute naloxone. As of June 2010, t...

Journal: :The Annals of pharmacotherapy 2006
Jennifer R Baker Al M Best Patricia A Pade Elinore F McCance-Katz

BACKGROUND Cardiac arrhythmias have been linked to treatment with methadone and levacetylmethadol. HIV-positive patients often have conditions that place them at risk for QT interval prolongation including HIV-associated dilated cardiomyopathy, coronary artery disease as a consequence of highly active antiretroviral (ARV) therapy-associated metabolic syndrome, and uncorrected electrolyte abnorm...

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