In order to contribute to the understanding of the biological properties of nafazatrom, an antithrombotic agent (NAP), we studied its effects on peroxidation of low density lipoproteins (LDL), lipid liposomes, heart homopgenate, and its interaction with alpha-tocopherol radical. NAP decreased the FeSO4 and H202-induced peroxidation of phosphatidylcholine liposomes and heart homogenate, and it d...

Vascular calcification is a complex biological process that is a hallmark of atherosclerosis. While macrocalcification confers plaque stability, microcalcification is a key feature of high-risk atheroma and is associated with increased morbidity and mortality. Positron emission tomography and X-ray computed tomography (PET/CT) imaging of atherosclerosis using (18)F-sodium fluoride ((18)F-NaF) h...

Aim: The aim of this study is to investigate the effects chitosan application on lung tissue in rats with experimental fluorine toxicity.
 Material and Method: In study, 21 healthy male wistar albino were used. Prior trial, acclimation was provided. 3 groups randomly generated a way that there 7 each group. These determined as control group (C), fluorosis (NaF) + (NaF+CS) group.
 Resu...

The current study was conducted to investigate the effect of sodium fluoride (NaF) on the oxidative stress and apoptosis as well as their relationship in the mouse liver by using methods of flow cytometry, quantitative real-time polymerase chain reaction (qRT-PCR), western blot, biochemistry and experimental pathology. 240 four-week-old ICR mice were randomly divided into 4 groups and exposed t...

A renewed interest has been recently developed for the highly sensitive bone-seeking radiopharmaceutical 18F-NaF. Aim of the present study is to evaluate the potential utility of quantitative analysis of 18F-NaF dynamic PET/CT data in differentiating malignant from benign degenerative lesions in multiple myeloma (MM). 80 MM patients underwent whole-body PET/CT and dynamic PET/CT scanning of the...

OBJECTIVE Titanium tetrafluoride (TiF4) has shown promising effect in preventing tooth lesions. Therefore, we compared the cytotoxicity of TiF4 with sodium fluoride (NaF) (already applied in Dentistry) considering different fluoride concentrations, pH values and experimental models. MATERIALS AND METHODS Step 1) NIH/3T3 fibroblasts were exposed to mediums containing NaF or TiF4 (from 0.15 to ...

      The effects of hydroalcoholic extract (HE) of Curculigo orchioides Gaertn. rhizome (Hypoxidaceae) and its alkaloidal and non-alkaloidal fractions (AF) and (NAF) were evaluated in carrageenan-induced paw edema experimental models of inflammation. The oral administration of HE, their AF and NAF fractions were used at doses of 100, 300 and 500 mg/kg. The effect produced by the HE, A...

Large earthquakes that have occurred along the North Anatolian Fault (NAF) were analysed to elaborate time frame of future large near İstanbul. The historical earthquake catalog was compiled covered 1 nearly complete and 2 fully failures NAF between 1250 2000 AD. These data used investigate space-time systematics M ≥ 7.0 earthquakes. catalogue identified an east-to-west decelerating domino-like...

UNLABELLED Under Medicare's Coverage with Evidence Development policy, PET using (18)F-sodium fluoride (NaF PET) to identify osseous metastasis became a covered service if prospective registry data were collected. The National Oncologic PET Registry (NOPR) developed a NaF PET registry built on the foundation of its prior registry for PET with (18)F-FDG. Men with prostate cancer represented 72% ...