This paper outlines a novel methodology for calibrating building energy simulation (BES) models through the use of an evidence-based approach and detailed simulation modelling. The proposed calibration methodology is applied to a 30,000m 2 office building. The case study illustrates the results of calibrating the model to Energy Monitoring System (EMS) and other readily accessible data. The pap...

quinolone antibacterials are one of the most important classes of pharmacological agents known as potent inhibitors of bacterial dna gyrase and topoisomerase iv that efficiently inhibit dna replication and transcription by generating several double-stranded dna break. some quinolone derivatives demonstrated inhibitory potential against eukaryote topoismarase ii and substantial dose-dependent cy...

N,N-diethylethanaminium-2-(sulfooxy) ethyl sulfate was synthesized and used as  an efficient, green, and recyclable catalyst and solvent for the nitration of aromatic compounds by nitric acid at 80oC