N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN), which specifically induces bladder tumors, was shown to be mutagenic to Salmonella typhimurium strains TA 1535 and TA100 in the presence of an S-9 mix prepared from the liver of rats treated with polychlorinated biphenyl. Reduced nicotinamide adenine dinucleotide was a more effective cofactor than reduced nicotinamide adenine dinucleotide phosphate i...

In the title mol-ecule, C(26)H(25)Br(3)N(2), a dihedral angle of 6.15 (10)° is present between the carbazole and benzene ring systems with an E conformation about the C=C bond [1.335 (4) Å]. The butyl group is almost perpendicular to the carbazole plane [C-N-C-C torsion angle = -98.7 (3)°]. In the crystal, supra-molecular double chains along [-7,18,-16] are formed via C-H⋯Br and π-π inter-actio...

In the title compound {systematic name: cis-bis-[4-amino-N-(pyrimidin-2-yl)benzene-sulfonamidato-κ(2)N,N']bis-(butyl-amine-κN)copper(II) penta-hydrate}, [Cu(C(10)H(9)N(4)O(2)S)(2)(C(4)H(11)N)(2)]·5H(2)O or [Cu(sdz)(2)(ba)(2)]·5H(2)O [ba is butyl-amine and sdz = sulfadiazine(1-)], the copper(II) cation is six-coordinated by four N atoms of two sulfadiazine ligands and two N atoms of butyl-amine ...

a mild and efficient method has been developed for the preparation of substituted coumarins from reaction of various phenols with different β-ketoesters via pechmann condensation in the presence of brønsted acidic ionic liquid (n-(4-sulfonic acid) butyl triethylammonium hydrogen sulfate) as an effective catalyst under solvent-free conditions. different phenols reacted with ethyl acetoacetate to...