The anthelmintic activity of alkaloid extracted from the stem bark of Afzelia africana was evaluated in-vivo in rats experimentally infected with Nippostrongylus braziliensis. The alkaloids was obtained after partitioning the crude methanolic extract of the plant powdered material in petroleum ether, chloroform and N-butanol as solvent and subsequently subjecting them to phytochemical screening...

BACKGROUND Crude glycerol in the waste stream of the biodiesel production process is an abundant and renewable resource. However, the glycerol-based industry is usually afflicted by the cost for refinement of crude glycerol. This issue can be addressed by developing a microbial process to convert crude glycerol to value-added chemicals. In this study, Escherichia coli was implemented for the pr...

The aim of this reasearch is to investigate the effects of various extracts of Tongkat Ali on uric acid excretion and renal function in rats with hyperuricemia. Sprague dawley male rats were fed with yeast extract, adenine and potassium oxonate to make the model of rats with hyperuricemia. With the animal model being made, Rats were given various extracts from Tongkat Ali for 14 d. Then, uric a...

In this study, we performed a phenotypic screening in human endothelial cells exposed to oxidized low density lipoprotein (an in vitro model of atherosclerotic endothelial dysfunction) to identify the effective compounds in Shixiao San. After investigating the suitability and reliability of the cell-based screening method using atorvastatin as the positive control drug, this method was applied ...

BACKGROUND Multiple Chemical Sensitivity (MCS) is a chronic condition characterized by reports of recurrent symptoms in response to low level exposure to various chemical substances. Recent findings suggests that dysregulation of the immune system may play a role in MCS pathophysiology. OBJECTIVES The aim of this study was to examine baseline and low dose n-butanol-induced upper airway inflam...

The effects of five fuel alcohols (methanol, ethanol, 1-propanol, iso-butanol and n-butanol) on the natural attenuation of benzene were compared using a previously developed numerical model (General Substrate Interaction Module--GSIM) and a probabilistic sensitivity analysis. Simulations with a 30 gal dissolving LNAPL (light non-aqueous phase liquid) source consisting of a range of gasoline ble...

Phlomis crinita Cav., is a Lamiaceae very widespread in the North-West of Algeria (Chlef), but little studied on chemical and pharmacological levels; for this, phytochemical screening, then dosage total phenolic compounds (TPC), flavonoids (TFL) condensed tannins (TCN) obtained by (02) methods (reflux ultrasonic bath), followed an evaluation antibacterial activities antioxidants, were carried o...

The antioxidant activities of the ethanol, petroleum ether, ethyl acetate, n-butanol and water extract fractions from the seeds of papaya were evaluated in this study. The ethyl acetate fraction showed the strongest DPPH and hydroxyl free radical-scavenging activities, and its activities were stronger than those of ascorbic acid and sodium benzoate, respectively. The n-butanol fraction demonstr...

BACKGROUND A number of medicinal plants and there compounds played a major role in the treatment of hepatic disorders. They were widely used for the treatment of these disorders, and oxidant stress injury was one of the liver injury mechanisms. The present study evaluated the antioxidant activity and the hepatoprotective effect of each extracts of Phlomis maximowiczii. MATERIALS AND METHODS T...

The alcohol and n-butanol extract of Potentilla anserine L. significantly protects myocardium from acute ischemic injury. However, its effects on rat hippocampal neurons and the mechanism of protection remain unclear. In this study, primary cultured hippocampal neurons from neonatal rats were incubated in 95% N2 and 5% CO2 for 4 hours. Results indicated that hypoxic injury decreased the viabili...