BACKGROUND/OBJECTIVES As a proinflammatory cytokine, interleukin-17 (IL-17) contributes to the inflammation of many autoimmune diseases. We examined IL-17 levels in serum and tissues from patients with chronic hepatitis B virus infection (HBV), and especially evaluated the role of IL-17 in the pathogenesis and progression of liver fibrosis. MATERIALS AND METHODS Whole venous blood was obtaine...

Abstract C 17 H 18 F 6 N O, monoclinic, P 2 1 / n (no. 14), a = 9.9491(11) Å, b 18.1523(17) c 11.7703(15) β 113.473(14)°, V 1949.8(4) Å 3 , Z 4, R gt ( ) 0.0606, wR ref 0.1876, T 169.99(10) K.

objective: premenstrual syndrome (pms) is a cluster of physical and emotional changes that typically begins several days before the menstrual period that disappears quickly after menstruation. it seems that cooccurrence of depression increases the risk and severity of this syndrome. in this cross-sectional research, we evaluated an association between pms and depression in medical students. met...

Original meiotic or mitotic chromosome counts are presented for 17 species in 12 families of angiosperms from Iran. Chromosome counts for Amberboa nana, n=16 (Asteraceae) and Camelina rumelica subsp. transcapica, n=13 (Brassicaceae) are repoted for the first time. Chromosome numbers for six species including: Rhagadiolus stellatus (n=5), Campanula raponcoloides (n=34), Campanula trachelium (n=1...

PURPOSE We determined the maximum-tolerated dose (MTD) and the dose-limiting toxicities (DLT) of 17-allylamino-17-demethoxygeldanamycin (17-AAG) when infused on days 1, 8, and 15 of a 28-day cycle in advanced solid tumor patients. We also characterized the pharmacokinetics of 17-AAG, its effect on chaperone and client proteins, and whether cytochrome P450 (CYP) 3A5 and NAD(P)H:quinone oxidoredu...