نتایج جستجو برای: myxobacterium stigmatella eracta wxnxj b
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Covering: 1994 to 2008. The disorazoles comprise a family of 29 closely related macrocyclic polyketides isolated in 1994 from the fermentation broth of the gliding myxobacterium Sorangium cellulosum. Disorazoles A1, E and C1 have shown exceptional biological activites toward inhibiting the proliferation of human cancer cell lines in picomolar and nanomolar concentrations through the disruption ...
A reduction in the cellular levels of the cyclin kinase inhibitor p27(kip1) is frequently found in many human cancers and correlates directly with patient prognosis. In this work, we identify argyrin A, a cyclical peptide derived from the myxobacterium Archangium gephyra, as a potent antitumoral drug. All antitumoral activities of argyrin A depend on the prevention of p27(kip1) destruction, as ...
The desert, which covers around one-third of Earth’s continental surface, is defined as the harshest terrestrial environment and comprises a highly extensive biome ecosystem. Microorganisms are key drivers that maintain integrity desert ecosystems. Over past few decades, desertification has increased owing to changes in rainfall patterns global warming, characterized by land degradation, loss m...
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