AIM To examine the analgesic effect of alkaloids in Myristica fragrans seed in a mouse model of acetic acid-induced visceral pain. METHODS Alkaloids were extracted from ground nutmeg seed kernels with 10% acetic acid in 95% ethyl alcohol. Visceral pain was induced in male and female BALB/c mice by intraperitoneal injection of 0.6% acetic acid. Analgesic effect of alkaloids (0.5 gram or 1 gram...

Abstract This review aimed to assess the antioxidant properties of safrole, myristicin, and terpineol from Myristica fragrans Houtt. Safrole exhibited high cytotoxic activities against numerous cancer cell lines also shown able suppress tumor angiogenesis. Myristicin is increase activity glutathione peroxidase (GPX), reductase (GR) or glutathione-disulfide-reductase (GSR), superoxide dismutase ...

BACKGROUND Spices are considered as sexual invigorators in the Unani System of Medicine. In order to explore the sexual function improving effect of Myristica fragrans Houtt. (nutmeg) and Syzygium aromaticum (L) Merr. & Perry. (clove) an experimental study was conducted in normal male mice. METHODS The extracts (50% ethanolic) of nutmeg and clove were administered (500 mg/kg; p.o.) to differe...

Germplasm conservation in the form of seed is convenient and most cost-effective ex situ conservation method for plant species producing orthodox seeds. Several species of plantation crops and spices produce non-orthodox seeds, which exhibit intermediate or recalcitrant seed storage behaviour. Storage of these species requires the use of in vitro conservation techniques for shortto medium-term ...