To evaluate the biological functions of myogenic regulatory factors, we have examined the effects of ectopic expression of MyoD and Cx43 genes in the fibroblasts on the differentiation of myoblast in vitro. The expression of MyoD and Cx43 in the transfectants was confirmed by RT-PCR and Western blot. More than 50% of fibroblasts transfected with MyoD or both MyoD and Cx43 genes displayed typica...

Statin therapy is effective at reducing cardiovascular event rates among those with prior myocardial infraction, stroke, diabetes, or overt hyperlipidemia, and current guidelines strongly recommend lipid-lowering therapy among these patient groups as an adjunct to aggressive lifestyle interventions. However, of the nearly 1.7 million heart attacks and strokes that occur annually in the United S...

Background: The role of D-dimer and H-FABP as diagnostic markers in myocardial infarction (MI) is still a question. We aim to investigate the usefulness determination for evaluation patients. Methods: Forty patients with MI 40 controls mean age (57.37 ± 8.27), (57.47±8.329) were conducted. D-dimer, H-FABP, troponin I tests determinate at admission using Up-Converting Phosphor Quantitative Immun...

conclusions although relative risk per 10 µg/m3 is low and sometimes mortality and morbidity attributable to pollutant seems slight because of sensitive and large population exposed to air pollutants, burden of disease associated with air pollution will be great. therefore, authorities should apply necessary actions and efforts based on comprehensive scientific researches in order to control ai...

Giannopoulos et al 1 report that delivering a stand-alone educational programme following myocardial infraction (MI) reduces the risk of cardiovascular events. This single-centre trial, based in university hospital Athens, randomised 329 postmyocardial patients to either an 8-week structured education plus usual care (intervention) or (control). The authors reported intervention consisted 10 ho...

BACKGROUND Intensive care is a crucial component of hospital care, reserved for patients with potentially recoverable conditions who can benefit from invasive treatment. However, in developing countries like Nepal, resources and availability intensive become hurdles delivering healthcare. This study presents the pattern admission outcome patients' management general unit (ICU) this tertiary cen...

INTRODUCTION AND OBJECTIVES Myocardial contrast echocardiography (MCE) is useful for predicting the functional recovery of akinetic segments in patients undergoing primary angioplasty after acute myocardial infraction (AMI). Recently, parametric imaging-based quantitative MCE has been developed for measuring perfusion. Our aims were: a) to measure perfusion in akinetic myocardial segments in pa...

Abstract Aims The Academic Research Consortium for High Bleeding Risk (ARC-HBR) presents a bleeding risk assessment in antithrombotic therapy patients post percutaneous coronary intervention (PCI). In Japanese patients, heart failure (HF), peripheral vascular disease, and frailty are established as factors addition to ARC-HBR. However, it is unknown whether left ventricular function or severity...