BACKGROUND Differences in life expectancy (LE) between social groups in a specific country are a fundamental measure of health inequalities within that country. Constant monitoring of these differences provides important information on the population's general health. The purpose of the present study is to explore and quantify the socio-economic differences in LE in Germany, focussing on a topi...

BACKGROUND Telomeres are repetitive, gene-poor regions that cap the ends of DNA and help maintain chromosomal integrity. Their shortening is caused by inflammation and oxidative stress within the cellular environment and ultimately leads to cellular senescence. Shortened leukocyte telomere length is hypothesized to be a novel biomarker for age and age-related diseases, yet reports on its associ...

Major depressive disorder is associated with an elevated risk of numerous metabolic disturbances, including obesity, metabolic syndrome, insulin-dependent diabetes mellitus type II, and death after myocardial infarction. Several recent papers also indicate that disturbances of mood may alter peripheral signaling pathways that regulate metabolic processes, including those involving leptin and gh...

Background: Patients with diabetes mellitus undergoing coronary artery bypass graft surgery (CABG) have increased perioperative morbidity and mortality. Tighter glycemic control with an insulin infusion immediately after an acute myocardial infarction has been found to reduce mortality among patients with hyperglycemia. It is unknown whether diabetic patients undergoing CABG would also benefit ...

The present study aims to find out prognostic importance of stress hyperglycemia and incidence of various complications in patients of Acute myocardial infarction (MI) without diabetes mellitus. Method: We studied 50 patients admitted with acute MI without previous diabetes mellitus. Blood glucose level were estimated at time of admission and regularly thereafter. Glycosylated hemoglobin was es...

The leading cause of death in patients with diabetes mellitus in the West is ischemic heart disease. Both in Japan and Asian countries, mortality due to ischemic heart diseases is on the rise and is most significant as the cause of death in diabetic patients. Ischemic heart disease seen in diabetic patients is associated with severe coronary artery lesions, with relatively few symptoms; and its...

BACKGROUND The classification of myocardial infarction into 5 types was introduced in 2007. The prognostic impact of this universal definition, with particular focus on type 2 myocardial infarction, has not been studied prospectively in unselected hospital patients. METHODS During a 1-year period, all hospitalized patients having cardiac troponin I measured were considered. The diagnosis of a...

OBJECTIVE The aim of the study was to examine the prospective association between life satisfaction and risk of type 2 diabetes mellitus, myocardial infarction, stroke, and cancer. Previous studies suggested that psychosocial factors may affect the development of chronic diseases but the impact of positive attitudes, in particular life satisfaction, is yet to be determined. METHODS The analys...

Contraceptive Users To the Editor: We read with interest the article by Siritho et al on ischemic stroke risk in oral contraceptive users.1 This case-control study seems well conducted, but the conclusion is not consequential to the results obtained. The conclusion of a study is of crucial importance when it deals with the practical implication of the study itself, which, in the case in point, ...