The present study was designed to investigate whether Sida rhombifolia Linn (Malvaceae), a natural herb, would attenuate the acute myocardial infarction in isoproterenol (ISP)-treated rat model via maintaining cardiac function and activities of endogenous antioxidant enzymes. Heart tissue enzyme analysis in albino (Wistar) male rats, such as LPO, GSH, GPX, GST, SOD, CAT, CK-MB, MDA and biochemi...

Acute coronary syndrome (ACS) refers to any constellation of clinical symptoms that are compatible with acute myocardial ischemia. ACS is divided into ST- elevated myocardial infarction (STEMI), non-ST elevated myocardial infarction (NSTEMI), and unstable angina (UA). STEMI results from complete and prolonged occlusion of an epicardial coronary blood vessel and is defined based on ECG criteria....

Clinicians have long recognized that acute myocardial infarction (MI) can occur in the absence of atherothrombosis . The Universal Definition MI Global Taskforce introduced a classification system 2007 (and reaffirmed 2012) defined type 2 (following standard diagnostic criteria) as occurring due to an imbalance oxygen supply and/or demand not caused by atherosclerotic plaque disruption. Neverth...

Accurate recognition of signs and symptoms and prompt diagnosis of myocardial infarction are essential for preserving myocardial function and saving lives. However, measurements of cardiac enzymes such as creatine kinase, lactate dehydrogenase, and their isoenzymes do not always provide accurate clinical diagnosis, particularly in patients with other concomitant diseases. Recently, alternative ...

We examined the kinetics of the catalytic activities of aspartate aminotransferase (AST, EC 2.6.1.1) isoenzymes in serum of 28 patients with myocardial infarction who were to receive either intracoronary urokinase--reperfusion angiographically proved--or conventional therapy (control group). Cytosolic (soluble) AST (s-AST) activity in serum increased rapidly immediately after recanalization, re...

Carvacrol (CAR), a naturally occurring phenolic monoterpene, has been shown to possess diverse biological activities. The present study was undertaken to evaluate the cardioprotective potential of CAR against myocardial ischemic damage in a rat model of acute myocardial infarction. CAR significantly diminished the infarct size and myocardial enzymes including creatine kinase (CK), the MB isoenz...