the respiratory tract contains numerous peptides secreted from special pulmonary epithelial cells whichare called endocrine cells. the function of neuroendocrine cells is modulated by amines. serotonin has strong vasomotor and bronchomotor effects in the airway mucosa. the objective of this study was to determine presence and distribution of serotonin-positive endocrine cells in respiratory tra...

introduction: type i diabetes mellitus is caused by autoimmune destruction of the insulin-producing β-cells. a new potential method for curing the disease is transplantation of differentiated insulin- secreting cells from human embryonic stem cells. methods: human embryonic stem cell lines (royan h1) were used to produce embryoid bodies. differentiation carried out by growth factor-mediated sel...

Neural stem cells (NSCs) as a heterogeneous multipotent and self- renewal population are found in different areas in the developing mammalian nervous system, as well as the sub-ventricular zone (SVZ) and the hippocampus of the adult brain. NSCs can give rise to neurons, astrocytes and oligodendrocytes. The aim of this study was to differentiate neural stem cells into noradrenergic–like cells in...