introduction: the aim of this study is to investigate the effect of one nitric oxide inhibitor on the thickness and number of circular smooth muscle cells of pylor in rat embryo. material and methods: to determine the influence of nitric oxide reduction on the muscular layer of pylor in rat embryo, in the present study, pregnant sprague-dawley rats received the no synthase inhibitor n-nitro-l-a...

purpose prolonged physical exercise results in transient elevations of biochemical markers of muscular damage. this study examined the effect of short-term maximal exercise on these markers, homocysteine levels (hcy), and total antioxidant status (tas) in trained subjects. methods eighteen male football players participated in this study. blood samples were collected 5-min before and 3-min afte...

The objective of this study was to establish the optimum protocol for the isolation and culture of porcine muscle satellite cells. Mononuclear muscle satellite cells are a kind of adult stem cell, which is located between the basal lamina and sarcolemma of muscle fibers and is the primary source of myogenic precursor cells in postnatal muscle. Muscle satellite cells are a useful model to invest...

BACKGROUND: Muscle injuries are a common manifestation of exercise and non-mechanical factors such as drugs, genetic defects, systemic diseases. Despite their clinical importance, the cellular molecular mechanisms muscle injury repair poorly understood, which hamper development effective interventions. OBJECTIVE: This review is an attempt to recognize basic principles skeletal regeneration proc...

The evidence that regular physical exercise reduces the risk of developing cancer is well described. However, interaction between and not fully clarified yet. Several myokines released by skeletal muscle appear to have a direct anti-tumour function. There are few data on myokine secretion after in patients with advanced tumours. Pancreatic (PC) very aggressive usually fatal cancer. To investiga...

Background: Adenosine plays the role of regulating cell differentiation, proliferation, and apoptosis in various kinds cells through B-cell lymphoma 2 (BCL2) pathway. Objectives: Since anti-apoptotic expression a controlling some lines, this study was designed to investigate whether adenosine analogue, NECA (non-selective receptors agonist), selective A2B receptor antagonist, PSB 603, A2A agoni...

In this research, Yang et al. have done single cell analysis of obesity and exercise interactions to determine the response mesenchymal stem cells (MSCs) white adipose skeletal muscle tissue in mice models. The study concluded that, reverse effects on extracellular matrix (ECM) genes involved circadian rhythms MSCs.

Background and Aims: During vascular calcification (VC), a cardiovascular complication of atherosclerosis, smooth muscle cells (VSMCs) undergo an osteogenic switch secrete heterogeneous population extracellular vesicles (EVs) involved in inflammation oxidative stress. The objective our study is to determine the role mechanism action EVs propagation stress during VC.