incorporation of functional foods and nutraceuticals such as carotenoids which suffer from poor water solubility and low bioavailability into nano-sized delivery systems can improve their solubility, stability and oral bioavailability. the aim of this study was to prepare β-carotene nanodispersion and investigate the effects of preparation parameters by means of response surface methodology usi...

conclusions we found ccd and rsm very effective in optimizing hib culture conditions, and hib biomass production was greatly influenced by ph and incubation temperature. therefore, optimization of the growth factors to maximize hib production can lead to 1) an increase in bacterial biomass and prp productions, 2) lower vaccine prices, 3) vaccination of more susceptible populations, and 4) lower...

This paper addresses the problems caused by an inappropriate selection of sliding surface parameters in fuzzy sliding mode controllers via an optimization approach. In particular, the proposed method employs the parallel distributed compensator scheme to design the state feedback based control law. The controller gains are determined in offline mode via a linear quadratic regular. The particle ...

Research on waste tire pyrolysis carbon black (PCB) in bitumen mixtures indicates that it has excellent high-temperature rutting resistance; however, the degradation of low-temperature crack resistance and water stability PCB-modified asphalt limits its wide application. Therefore, hot-mix (HMA) were enhanced by addition chicken feather (WCF). Based response surface methodology (RSM), a varianc...

this paper describes optimization method that combines the plackett-burman design, a factorial design and the response surface method, which were used to optimize the medium for the production of l-asparaginase by serratia marcescens sb08. four medium factors, from out of 11 medium factors, were screened by plackett-burman design experiments and subsequent optimization process to find out the o...

permanent magnet synchronous motors are efficient motors, which have widespread applications in electric industry due to their noticeable features. one of the interesting applications of such motors is in underwater vehicles. in these cases, reaching to minimum volume and high torque of the motor are the major concern. design optimization can enhance their merits considerably, thus reduce volum...