Dietary red pepper suppresses energy intake and modifies macronutrient intake. We have investigated whether a stimulus in the mouth and the sensation of spiciness are necessary for red pepper-induced changes in energy and macronutrient intake in human volunteers. In a preliminary test, sixteen Japanese male volunteers tasted samples of a soup with graded doses of red pepper in order to define a...

BACKGROUND Treatment for tumors of the oral cavity and the oropharynx disrupts normal swallow function. The ability for oral diet postoperatively varies and may be influenced by surgery and patient-related factors. METHODS In all, 114 patients treated with surgery with and without chemoradiotherapy for advanced oral/oropharyngeal cancer were recruited. Clinicopathologic tumor parameters and r...

abstract fixed drug eruption (fde) is a unique type of cutaneous drug reaction that typically recurs in the identical locations on re-exposure to the attributed drug. fde is characterized by the appearance of a single or multiple sharply demarcated violaceous erythematous plaques which heal with residual hyperpigmentation. a 27-year-old woman presented with multiple dark patches over her eyelid...

Background Chili is the most heavily and frequently consumed spice, either as a flavouring or colouring agent, it also major source of pro-vitamin A, vitamin E C. The main capsinoidcapsaicinoid found in chili peppers capsaicin. It has been demonstrated that capsaicin acts cancer-suppressing agent through its antioxidant anti-inflammatory effects, by blocking several signal transduction pathways...

Evidence of associations between single nutrients and head and neck cancer is still more limited and less consistent than that for fruit and vegetables. However, clarification of the protective mechanisms of fruit and vegetables is important to our understanding of head and neck cancer etiology. We investigated the association between vitamin C intake from natural sources and cancer of the oral...