Uterine leiomyomas are the most prevalent benign tumor type in women of reproductive age and are one of the most common indications for hysterectomy. The expression of five angiogenic factors, adrenomedullin (ADM), vascular endothelial growth factor (VEGF), acidic fibroblast growth factor, basic fibroblast growth factor, and platelet-derived endothelial cell growth factor/thymidine phosphorylas...

Mesenchymal tumor of the esophagus is rare, and the most common mesenchymal tumor of the esophagus is leiomyoma [1-3]. The incidence of esophageal leiomyoma from autopsy cases ranges from 0.005 to 5% [2, 3]. Although detailed histopathological examination of autopsy and surgically resected case series demonstrated that its incidence is higher at 7.9% [1]. This disease is typically found in pati...

In order to ensure safe magnetic resonance-guided, high-intensity focused, ultrasound ablation of uterine leiomyomas, the ultrasound beam path should be free of intervening scar and bowel. Pre-treatment MRI of a 9-cm long and 7.7-cm wide leiomyomatous uterus in a 39-year-old woman with menorrhagia and abdominopelvic pain initially demonstrated a focused ultrasound treatment path without a bowel...

Cytogenetic studies were carried out on a low-grade metastatic uterine leiomyosarcoma and on a large degenerating uterine leiomyoma. The leiomyosarcoma and leiomyoma were hyperdiploid and hypodiploid, respectively, and both tumors contained multiple consistent chromosome aberrations. In the patient with leiomyosarcoma, flow cytometric studies of proliferative foci from a previously resected ute...

Multiple circular or oval pulmonary densities on chest roentgenogram most commonly represent neoplastic metastases. This radiographic picture may also be seen in other tumors (lymphoma, myeloma), infectious diseases (especially tuberculosis and fungal chest diseases), immunologic disorders (Wegener’s granulomatosis and rheumatoid lung), mucoid impaction, pneumoconiosis, A-V fistulae, multiple b...

The diagnosis of uterine smooth muscle neoplasms by light microscopy is difficult. Multiple classification schemes have been proposed based on mitotic rate, nuclear atypia, and the presence or absence of necrosis. None of these classification systems has been entirely successful. This study was undertaken to evaluate the use of selected immunohistochemical and histochemical markers in different...

BACKGROUND High-intensity focused ultrasound (HIFU) is a highly precise medical procedure used locally to heat and destroy diseased tissue through ablation. This study intended to review HIFU in uterine fibroid therapy, to evaluate the role of HIFU in the therapy of leiomyomas as well as to review the actual clinical activities in this field including efficacy and safety measures beside the pub...