Al-MCM-41 nanoreactors is found to be a remarkable efficient catalyst for one-pot multicomponent cyclocondensation of benzil, aniline or ammonium acetate and aromatic aldehydes for the synthesis of polysubstituted imidazoles under solvent-free conditions. The reaction was efficiently promoted by 10 mg nano-Al-MCM-41 and the heterogeneous catalyst was recycled for four runs in this reaction with...

Solid-state polymer electrolytes offer a safer alternative to traditional lithium-ion batteries based on organic electrolytes. The focus is here imidazole(Im)-functionalized electrolytes, where the Im ligand promotes salt dissolution, while its functionalization allows tuning dynamic interactions between cations in solution and tethered backbone. Although careful choice of backbone linker funct...

interest in agrochemicals and drugs. Aryl group substituted pyrazoles and imidazoles, in particular, have been studied because their biological activities are strongly dependent on their substituents on the pyrazole ring system. 1,5-Diaryl substituted pyrazole (SR141716A, 1), which has a hydrazide group on the 3-position of the pyrazole ring, has recently been synthesized and identified as the ...

In the past few years multi component reactions have captured the attention of synthetic chemists as they provide  easy  access  to diverse  complex  organic molecules through  carbon -  carbon   and  carbon - heteroatom  bond  formations  in tandem manner with simple easy  to carry out  reaction  conditions in short  time. 1,8-dioxo-octahydroxanthene is a significant class of oxygen containing...

An alternative strategy for the synthesis of 1-aryl- and 1-alkyl-2-methylsulfanyl-4-(4-fluorophenyl)-5-(pyridin-4-yl)imidazoles as potential p38α mitogen-activated protein kinase inhibitors is reported. The regioselective N-substitution of the imidazole ring was achieved by treatment of α-aminoketones with different aryl or alkyl isothiocyanates. In contrast to previously published synthesis ro...

A general approach for the synthesis of bis(imidazolium) dichloride salts from imidazoles and dichloroalkanes is reported. Typical limitations this reaction formation methylene-bridge...