Copyright © 2010 Frederick Furness Publishing 20 Chronic sinusitis is one of the most commonly diagnosed chronic illnesses, and approximately 10-15% of the European and US population suffer from chronic rhinosinusitis. Inflammation of the nasal mucosa (i.e. rhinitis), due to bacterial, fungal or viral infections, allergies, or exposure to inhaled irritants, leads to acute sinusitis and CRS. Chr...

purpose: to report a case of ciliary body medulloepithelioma presenting as granulomatous uveitis.   patient and finding: a 3-year-old girl presented with chronic granulomatous anterior uveitis in the right eye following unilateral cataract extraction and iol implantation which was unresponsive to topical steroids and intra-vitreal injection of vancomycin and triamcinolone acetonide. one month l...

The airway acts as the first defense against inhaled pathogens and particulate matter from the environment. One major way for the airway to clear inhaled foreign objects is through mucociliary clearance (MCC), an important component of the respiratory innate immune defense against lung disease. MCC is characterized by the upward movement of mucus by ciliary motion that requires a balance betwee...

A workshop/symposium on “Mucociliary and Cough Clearance (MCC/CC) as a Biomarker for Therapeutic Development” was held on October 21–22, 2008, in Research Triangle Park, NC, to discuss the methods for measurement of MCC/CC and how they may be optimized for assessing new therapies designed to improve clearance of airway secretions from the lungs. The utility of MCC/CC as a biomarker for disease ...

Recurrent lung infections and pneumonia are emerging as significant comorbidities in the HIV-infected population in the era of combination antiretroviral therapy (cART). HIV infection has been reported to suppress nasal mucociliary clearance (MCC). Since the primary components driving nasal MCC and bronchial MCC are identical, it is possible that bronchial MCC is affected as well. Effective MCC...

BACKGROUND Horses develop recurrent airway obstruction (RAO) that resembles human bronchial asthma. Differentiated primary equine bronchial epithelial cells (EBEC) in culture that closely mimic the airway cells in vivo would be useful to investigate the contribution of bronchial epithelium in inflammation of airway diseases. However, because isolation and characterization of EBEC cultures has b...

the aim of this retrospective statistical study was to determine the prevalcence and frequency of age and sex distributions of pemphigus disease. pemphigus disease classified as autoimmune bullous dermatoses which is a chronic mucocutaneous disease.this study was performed in razi hospital and department of oral pathology of dental school, tehran university of medical sciences. the most frequen...

Welding work is associated with the inhalation of fumes and accumulation of particulates in welders' lungs. It is assumed that particulates deposited in the respiratory system, mainly consisting of iron oxides, are eliminated by several mechanisms, such as muco-ciliary transport and macrophage phagocytosis. In their cross-sectional study of 42 Finnish shipyard arc welders, Kalliomäki et al. ind...

behçet’s disease (bd) which is classified among vasculitides is a systemic disease with various manifestations. its clinical course is characterized by attacks and remissions. till now, two nationwide surveys of bd from iran and japan and 4 major case series from turkey, korea, morocco and england have been reported. clinical picture of bd is dominated by mucous membrane manifestations, includi...