نتایج جستجو برای: mrp

تعداد نتایج: 2072  

2000
O. Spirina Y. Bykhovskaya A. V. Kajava T. W. O'Brien D. P. Nierlich E. B. Mougey B. Wittmann-Liebold N. Fischel-Ghodsian

It has been proposed that splice-variants of proteins involved in mitochondrial RNA processing and translation may be involved in the tissue speci®city of mitochondrial DNA disease mutations (Fischel-Ghodsian, 1998. Mol. Genet. Metab. 65, 97±104). To identify and characterize the structural components of mitochondrial RNA processing and translation, the Mammalian Mitochondrial Ribosomal Consort...

Journal: :Stroke 2014
Longting Lin Andrew Bivard Christopher R Levi Mark W Parsons

BACKGROUND AND PURPOSE Magnetic resonance perfusion (MRP) and computed tomographic perfusion (CTP) are being increasingly applied in acute stroke trials and clinical practice, yet the comparability of their perfusion values is not well validated. The aim of this study was to validate the comparability of CTP and MRP measures. METHODS A 3-step approach was used. Step 1 was a derivation step, w...

Journal: :RNA 2002
Xing Li Daniel N Frank Norman Pace Janice M Zengel Lasse Lindahl

RNase MRP is a ribonucleoprotein enzyme involved in processing precursor rRNA in eukaryotes. To facilitate our structure-function analysis of RNase MRP from Saccharomyces cerevisiae, we have determined the likely secondary structure of the RNA component by a phylogenetic approach in which we sequenced all or part of the RNase MRP RNAs from 17 additional species of the Saccharomycetaceae family....

2009
Wen-Qing Hu Chun-Wei Peng Yan Li

BACKGROUND To detect the expression of multidrug resistance molecules P-glycoprotein (P-gp), Lung resistnce protein (LRP) and Multidrug resistance-associated protein (MRP) and analyze the relationship between them and the clinico-pathological features. METHODS The expressions of P-gp, LRP and MRP in formalin-fixed paraffin-embedded tissue sections from 59 gastric cancer patients were determin...

2017
Shuhui Liu Kaitao Zhao Xi Su Lu Lu He Zhao Xianwen Zhang Yun Wang Chunchen Wu Jizheng Chen Yuan Zhou Xue Hu Yanyi Wang Mengji Lu Xinwen Chen Rongjuan Pei

An efficient clearance of hepatitis B virus (HBV) requires the coordinated work of both the innate and adaptive immune responses. MITA/STING, an adapter protein of the innate immune signaling pathways, plays a key role in regulating innate and adaptive immune responses to DNA virus infection. Previously, we identified an alternatively spliced isoform of MITA/STING, called MITA-related protein (...

Journal: :The Journal of biological chemistry 1990
J N Topper D A Clayton

RNase mitochondrial RNA processing (MRP) is a site-specific endoribonuclease located in both the nucleus and mitochondria of vertebrate cells. The enzyme is a ribonucleoprotein whose RNA component has been shown to be encoded by a nuclear gene. Because RNase MRP is particular in its substrate requirement, RNA-RNA interaction has been proposed as important for the cleavage reaction. A secondary ...

Journal: :Revista da Associacao Medica Brasileira 2013
Sônia Ferreira Lopes Toffoli Olavo Franco Ferreira Filho Dalton Francisco de Andrade

OBJECTIVE This paper proposes the unification of entrance exams to medical residency programs (MRP) in Brazil. Problems related to MRP and its interface with public health problems in Brazil are highlighted and how this proposal are able to help solving these problems. METHODS The proposal is to create a database to be applied in MRP unified exams. Some advantages of using the Item Response T...

Determination of mirtazapine during psychopharmacotherapy in biological fluids is essential to achieve successful therapy, to avoid toxicity related to drug interactions, genetic variability and poor compliance. A new, rapid and sensitive high-performance liquid chromatography method has been developed in human plasma for the determination of mirtazapine (MRP) and N-desmethylmirtazapine (NDM) t...

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