نتایج جستجو برای: mpss point
تعداد نتایج: 524861 فیلتر نتایج به سال:
This mini-review discusses the evolution of fluorescence as a tool to study living cells and tissues in vitro and the present role of fluorescent protein biosensors (FPBs) in microphysiological systems (MPSs). FPBs allow the measurement of temporal and spatial dynamics of targeted cellular events involved in normal and perturbed cellular assay systems and MPSs in real time. FPBs evolved from fl...
OBJECTIVES Non-invasive prenatal testing for fetal trisomy 21 (T21) by massively parallel shotgun sequencing (MPSS) is available for clinical use but its efficacy is limited by several factors, e.g. the proportion of cell-free fetal DNA in maternal plasma and sequencing depth. Existing algorithms discard DNA reads from the chromosomes for which testing is not being performed (i.e. those other t...
Microphysiological systems (MPSs) are in vitro models that can incorporate dynamic stimuli such as flow, pressure and contraction cell culture, enabling the formation of cellular architectures retrieving physiological function often absent conventional 2D-cell culture. MPS applications saw a substantial growth recent years, drawing attention from industry strategy to optimize pre-clinical drug-...
این پایان نامه در اولین گام اندازه های تغییر فنی، تغییر کارایی تکنیکی، تغییر کارایی مقیاس و تغییر بهره وری را بررسی می کند. سپس، یک مدل تابع تولید فرامرز برای شرکت ها در گروه های مختلف که دارای تکنولوژی های متفاوتی هستند، نمایش داده می شود. مدل فرامرز قادر است قابلیت مقایسه کارایی تکنیکی شرکت ها در تکنولوژی های مختلف را فراهم کند. در پایان، شرکت هایی که تحت تکنولوژی های متفاوت اما تحت یک فراتک...
کلاسی از مدلهای معرفی شده در تحلیل پوششی داده ها مدلهای ضربی نامیده می شود. که بوسیله بنکر و مین دیراتا نشان داده شده است. مرزهای تکه ای خطی به کار گرفته شده در dea معمولاً بوسیله یک مرز کاب داگلاس است جایگزین شده اند. بنکر و مین دیراتا با شناختن بهره ورترین الگوی اندازه مقیاس مدلی را معرفی کردند. بنکر و همکاران همچنین روش دو مرحله ای را برای شناسایی بازده به مقیاس (rts) در مدلهای چند هدفه ارائه...
Based on the matrix product state (MPS) formalism, we introduce an ansatz for capturing excited states in finite systems with open boundary conditions, providing a very efficient method computing, e.g., spectral gap of quantum spin chains. This can be straightforwardly implemented top existing density-matrix renormalization group or MPS ground-state code. Although this approach is built open-bo...
Deficiency of glycosaminoglycan (GAG) degradation causes a subclass of lysosomal storage disorders called mucopolysaccharidoses (MPSs), many of which present with severe neuropathology. Critical steps in the degradation of the GAG heparan sulfate remain enigmatic. Here we show that the lysosomal arylsulfatase G (ARSG) is the long-sought glucosamine-3-O-sulfatase required to complete the degrada...
An economic measure of scale efficiency is the ratio of the minimum average cost to the average cost at the actual output level of a firm. It is easily measured by the ratio of the total cost of this output under the constant and variable returns to scale assumptions. This procedure does not identify the output level where the average cost reaches a minimum. This paper proposes a nonparametric ...
Mitogen-Activated Protein Kinase Kinase Kinases (MAPKKKs) are important components of MAPK cascades, which are universal signal transduction modules and play important role in plant growth and development. In the sequenced Arabidopsis genome 80 MAPKKKs were identified and currently being analysed for its role in different stress. In rice, economically important monocot cereal crop only five MAP...
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